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Molbank 2015, 2015(4), M872; doi:10.3390/M872

(Z)-3-Amino-5-(pyridin-2-ylmethylidene)-2-thioxo-1,3-thiazolidin-4-one

1
Division of Gastroenterology and Hepatology, Mayo Clinic, 200 First St. SW, Rochester, MN 55905, USA
2
GlaxoSmithKline, Hvezdova 1734/2c, Prague 140 00, Czech Republic
3
Department of Pharmaceutical Chemistry and Pharmaceutical Analysis, Faculty of Pharmacy in Hradec Kralove, Charles University in Prague, Heyrovskeho 1203, Hradec Kralove 500 05, Czech Republic
4
Department of Inorganic and Organic Chemistry, Faculty of Pharmacy in Hradec Kralove, Charles University in Prague, Heyrovskeho 1203, Hradec Kralove 500 05, Czech Republic
5
Department of Analytical Chemistry, Faculty of Pharmacy in Hradec Kralove, Charles University in Prague, Heyrovskeho 1203, Hradec Kralove 500 05, Czech Republic
*
Author to whom correspondence should be addressed.
Received: 25 September 2015 / Revised: 27 October 2015 / Accepted: 2 November 2015 / Published: 4 November 2015
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Abstract

3-Aminorhodanine reacts with aldehydes to form either 5-[(aryl)alkylidene]-substituted products or Schiff bases or derivatives substituted at both the 3-amino group and the 5-methylene group, depending on the reaction conditions. In this note, synthesis and characterization of 3-amino-5-(pyridin-2-ylmethylidene)-2-thioxo-1,3-thiazolidin-4-one is reported. View Full-Text
Keywords: 3-aminorhodanine; aldehydes; condensation products 3-aminorhodanine; aldehydes; condensation products
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Hirsova, P.; Dolezel, J.; Kucerova-Chlupacova, M.; Kunes, J.; Pilarova, V.; Novakova, L.; Opletalova, V. (Z)-3-Amino-5-(pyridin-2-ylmethylidene)-2-thioxo-1,3-thiazolidin-4-one. Molbank 2015, 2015, M872.

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