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Int. J. Mol. Sci. 2007, 8(7), 606-617; doi:10.3390/i8070606
Article

Dinuclear Zinc (II) Complexes of Macrocyclic Polyamine Ligands Containing an Imidazolium Bridge: Synthesis, Characterization, and Their Interaction with Plasmid DNA

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Received: 6 March 2007; in revised form: 6 June 2007 / Accepted: 14 June 2007 / Published: 4 July 2007
(This article belongs to the Special Issue Nucleic Acid Derivatives in Emerging Technologies)
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Abstract: Two novel macrocyclic polyamine ligands and their dinuclear zinc (II)complexes were synthesized and characterized. Their interaction with plasmid DNA wasstudied by gel electrophoresis and fluorescence quenching experiment. The result showedthat these complexes could bind DNA efficiently under physiological conditions.
Keywords: 1,4,7,10-tetraazacyclododecane (cyclen); zinc (II) complexes; imidazolium; synthesis; DNA protection. 1,4,7,10-tetraazacyclododecane (cyclen); zinc (II) complexes; imidazolium; synthesis; DNA protection.
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Huang, J.; Huang, Q.-D.; Zhang, J.; Zhou, L.-H.; Li, Q.-L.; Li, K.; Jiang, N.; Lin, H.-H.; Wu, J.; Yu, X.-Q. Dinuclear Zinc (II) Complexes of Macrocyclic Polyamine Ligands Containing an Imidazolium Bridge: Synthesis, Characterization, and Their Interaction with Plasmid DNA. Int. J. Mol. Sci. 2007, 8, 606-617.

AMA Style

Huang J, Huang Q-D, Zhang J, Zhou L-H, Li Q-L, Li K, Jiang N, Lin H-H, Wu J, Yu X-Q. Dinuclear Zinc (II) Complexes of Macrocyclic Polyamine Ligands Containing an Imidazolium Bridge: Synthesis, Characterization, and Their Interaction with Plasmid DNA. International Journal of Molecular Sciences. 2007; 8(7):606-617.

Chicago/Turabian Style

Huang, Jun; Huang, Qing-Dong; Zhang, Ji; Zhou, Li-Hong; Li, Qiang-Lin; Li, Kun; Jiang, Ning; Lin, Hong-Hui; Wu, Jiang; Yu, Xiao-Qi. 2007. "Dinuclear Zinc (II) Complexes of Macrocyclic Polyamine Ligands Containing an Imidazolium Bridge: Synthesis, Characterization, and Their Interaction with Plasmid DNA." Int. J. Mol. Sci. 8, no. 7: 606-617.


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