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Int. J. Mol. Sci. 2007, 8(7), 705-713; doi:10.3390/i8070705
Communication

Solubilization of Single-walled Carbon Nanotubes with Single- stranded DNA Generated from Asymmetric PCR

1, 2, 1, 3, 2, 2, 2,* , 1,*  and 2
1 Department of Biochemistry, Nanjing University, Nanjing 210093, P. R. China 2 Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, P. R. China 3 The People’s Hospital of Jiangsu Province, Nanjing 210029, P. R. China
* Authors to whom correspondence should be addressed.
Received: 31 May 2007 / Revised: 29 June 2007 / Accepted: 13 July 2007 / Published: 23 July 2007
(This article belongs to the Special Issue Nucleic Acid Derivatives in Emerging Technologies)
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Abstract

Carbon nanotubes (CNTs) can be effectively dispersed and functionalized bywrapping with long single-stranded DNA (ssDNA) synthesized by asymmetric PCR. ThessDNA-CNTs attached on surface of glass carbon electrode made it possible forelectrochemical analysis and sensing, which was demonstrated by reduction of H2O2 onhemoglobin/ssDNA-CNTs modified electrodes. This research showed the potentialapplication of DNA-functionalised CNTs in construction of future electrochemicalbiosensors.
Keywords: Carbon nanotubes (CNTs); single-stranded DNA (ssDNA); asymmetric PCR; electrochemical biosensor Carbon nanotubes (CNTs); single-stranded DNA (ssDNA); asymmetric PCR; electrochemical biosensor
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Liang, Z.; Lao, R.; Wang, J.; Liu, Y.; Wang, L.; Huang, Q.; Song, S.; Li, G.; Fan, C. Solubilization of Single-walled Carbon Nanotubes with Single- stranded DNA Generated from Asymmetric PCR. Int. J. Mol. Sci. 2007, 8, 705-713.

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