Next Article in Journal
Heat Shock Proteins in Vascular Diabetic Complications: Review and Future Perspective
Next Article in Special Issue
Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils
Previous Article in Journal
Phylodynamic and Genetic Diversity of Canine Parvovirus Type 2c in Taiwan
Previous Article in Special Issue
Tunisian Milk Thistle: An Investigation of the Chemical Composition and the Characterization of Its Cold-Pressed Seed Oils
Article Menu
Issue 12 (December) cover image

Export Article

Open AccessReview
Int. J. Mol. Sci. 2017, 18(12), 2571; https://doi.org/10.3390/ijms18122571

Essential Oils from Neotropical Piper Species and Their Biological Activities

1
Programa de Pós-Graduação em Biotecnologia, Universidade Federal do Pará, Belém 66075-900, Brazil
2
Programa de Pós-Graduação em Química, Universidade Federal do Pará, Belém 66075-900, Brazil
3
Department of Chemistry, University of Alabama in Huntsville, Huntsville, AL 35899, USA
4
Aromatic Plant Research Center, 615 St. George Square Court, Suite 300, Winston-Salem, NC 27103, USA
*
Author to whom correspondence should be addressed.
Received: 31 October 2017 / Revised: 23 November 2017 / Accepted: 23 November 2017 / Published: 14 December 2017
(This article belongs to the Special Issue The Beneficial Effects of Plant Oil on Human Health)
View Full-Text   |   Download PDF [3801 KB, uploaded 14 December 2017]   |  

Abstract

The Piper genus is the most representative of the Piperaceae reaching around 2000 species distributed in the pantropical region. In the Neotropics, its species are represented by herbs, shrubs, and lianas, which are used in traditional medicine to prepare teas and infusions. Its essential oils (EOs) present high yield and are chemically constituted by complex mixtures or the predominance of main volatile constituents. The chemical composition of Piper EOs displays interspecific or intraspecific variations, according to the site of collection or seasonality. The main volatile compounds identified in Piper EOs are monoterpenes hydrocarbons, oxygenated monoterpenoids, sesquiterpene hydrocarbons, oxygenated sesquiterpenoids and large amounts of phenylpropanoids. In this review, we are reporting the biological potential of Piper EOs from the Neotropical region. There are many reports of Piper EOs as antimicrobial agents (fungi and bacteria), antiprotozoal (Leishmania spp., Plasmodium spp., and Trypanosoma spp.), acetylcholinesterase inhibitor, antinociceptive, anti-inflammatory and cytotoxic activity against different tumor cells lines (breast, leukemia, melanoma, gastric, among others). These studies can contribute to the rational and economic exploration of Piper species, once they have been identified as potent natural and alternative sources to treat human diseases. View Full-Text
Keywords: piperaceae; neotropics; antimicrobial; cytotoxic; antiprotozoal; anticholinesterase; anti-inflammatory; analgesic piperaceae; neotropics; antimicrobial; cytotoxic; antiprotozoal; anticholinesterase; anti-inflammatory; analgesic
Figures

Graphical abstract

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
SciFeed

Share & Cite This Article

MDPI and ACS Style

da Silva, J.K.; da Trindade, R.; Alves, N.S.; Figueiredo, P.L.; Maia, J.G.S.; Setzer, W.N. Essential Oils from Neotropical Piper Species and Their Biological Activities. Int. J. Mol. Sci. 2017, 18, 2571.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top