Recent Advances in Comprehending the Signaling Pathways Involved in the Progression of Breast Cancer
AbstractThis review describes recent advances in the comprehension of signaling pathways involved in breast cancer progression. Calcium sensing receptor (CaSR), caveolae signaling, signaling referred to hypoxia-inducing factors and disturbances in the apoptotic machinery are related to more general biological mechanisms and are considered first. The others refer to signaling pathways of more specific biological mechanisms, namely the heparin/heparin-sulfate interactome, over-expression of miRNA-378a-5p, restriction of luminal and basal epithelial cells, fatty-acid synthesis, molecular pathways related to epithelial to mesenchimal transition (EMT), HER-2/neu gene amplification and protein expression, and the expression of other members of the epithelial growth factor receptor family. This progress in basic research is fundamental to foster the ongoing efforts that use the new genotyping technologies, and aim at defining new prognostic and predictive biomarkers for a better personalized management of breast cancer disease. View Full-Text
Scifeed alert for new publicationsNever miss any articles matching your research from any publisher
- Get alerts for new papers matching your research
- Find out the new papers from selected authors
- Updated daily for 49'000+ journals and 6000+ publishers
- Define your Scifeed now
Nicolini, A.; Ferrari, P.; Diodati, L.; Carpi, A. Recent Advances in Comprehending the Signaling Pathways Involved in the Progression of Breast Cancer. Int. J. Mol. Sci. 2017, 18, 2321.
Nicolini A, Ferrari P, Diodati L, Carpi A. Recent Advances in Comprehending the Signaling Pathways Involved in the Progression of Breast Cancer. International Journal of Molecular Sciences. 2017; 18(11):2321.Chicago/Turabian Style
Nicolini, Andrea; Ferrari, Paola; Diodati, Lucrezia; Carpi, Angelo. 2017. "Recent Advances in Comprehending the Signaling Pathways Involved in the Progression of Breast Cancer." Int. J. Mol. Sci. 18, no. 11: 2321.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.