Next Article in Journal
1α,25(OH)2D3 Suppresses the Migration of Ovarian Cancer SKOV-3 Cells through the Inhibition of Epithelial–Mesenchymal Transition
Next Article in Special Issue
Impact of Phosphate, Potassium, Yeast Extract, and Trace Metals on Chitosan and Metabolite Production by Mucor indicus
Previous Article in Journal
Accumulation and Toxicity of Superparamagnetic Iron Oxide Nanoparticles in Cells and Experimental Animals
Previous Article in Special Issue
An Amphiprotic Novel Chitosanase from Bacillus mycoides and Its Application in the Production of Chitooligomers with Their Antioxidant and Anti-Inflammatory Evaluation
Article Menu
Issue 8 (August) cover image

Export Article

Open AccessArticle
Int. J. Mol. Sci. 2016, 17(8), 1243; doi:10.3390/ijms17081243

Femtosecond Laser Patterning of the Biopolymer Chitosan for Biofilm Formation

1
São Carlos Institute of Physics, University of São Paulo (USP), São Carlos 13566-590, SP, Brazil
2
Department of Materials Engineering, School of Engineering of São Carlos (USP), São Carlos 13563-120, SP, Brazil
3
Physics Department, Federal University of São Carlos (UFSCAR), São Carlos 13565-905, SP, Brazil
4
Faculdade de Ciencias Farmaceuticas, UNESP—Univ. Estadual Paulista, Campus Araraquara, Departamento de Analises Clinicas, Araraquara 14800-903, SP, Brazil
*
Authors to whom correspondence should be addressed.
Academic Editor: Hitoshi Sashiwa
Received: 16 June 2016 / Revised: 13 July 2016 / Accepted: 26 July 2016 / Published: 19 August 2016
(This article belongs to the Special Issue Chitins 2016)
View Full-Text   |   Download PDF [2990 KB, uploaded 19 August 2016]   |  

Abstract

Controlling microbial growth is crucial for many biomedical, pharmaceutical and food industry applications. In this paper, we used a femtosecond laser to microstructure the surface of chitosan, a biocompatible polymer that has been explored for applications ranging from antimicrobial action to drug delivery. The influence of energy density on the features produced on chitosan was investigated by optical and atomic force microscopies. An increase in the hydrophilic character of the chitosan surface was attained upon laser micromachining. Patterned chitosan films were used to observe Staphylococcus aureus (ATCC 25923) biofilm formation, revealing an increase in the biofilm formation in the structured regions. Our results indicate that fs-laser micromachining is an attractive option to pattern biocompatible surfaces, and to investigate basic aspects of the relationship between surface topography and bacterial adhesion. View Full-Text
Keywords: fs-laser micromachining; micropatterning; chitosan; bacterial growth fs-laser micromachining; micropatterning; chitosan; bacterial growth
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Estevam-Alves, R.; Ferreira, P.H.D.; Coatrini, A.C.; Oliveira, O.N.; Fontana, C.R.; Mendonca, C.R. Femtosecond Laser Patterning of the Biopolymer Chitosan for Biofilm Formation. Int. J. Mol. Sci. 2016, 17, 1243.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top