Catalpol Ameliorates Sodium Taurocholate-Induced Acute Pancreatitis in Rats via Inhibiting Activation of Nuclear Factor Kappa B
Abstract
:1. Introduction
2. Results and Discussion
2.1. Results
2.1.1. Preliminary Study
2.1.2. Effect of Catalpol on STC-Induced AP in Vivo
2.1.3. Effect of Catalpol on STC-Induced AP in Vitro
2.2. Discussion
3. Experimental
3.1. Animals and Main Materials
3.2. Induction of Experimental Design
3.3. Isolation of Pancreatic Acinar Cells
3.4. Determination of Serum Amylase, Lipase and Serum Proinflammatory Cytokines
3.5. Histological Examination
3.6. Measurement of Myeloperoxidase Activity
3.7. Quantitative Real-Time PCR
3.8. Western Blot Analysis
3.9. Immunohistochemistry
3.10. Quantification of Cell Viability
3.11. Statistical Analysis
4. Conclusions
Acknowledgments
Author Contributions
Conflicts of Interest
References
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Xiao, W.Q.; Yin, G.J.; Fan, Y.T.; Qiu, L.; Cang, X.F.; Yu, G.; Hu, Y.L.; Xing, M.; Wu, D.Q.; Wang, X.P.; et al. Catalpol Ameliorates Sodium Taurocholate-Induced Acute Pancreatitis in Rats via Inhibiting Activation of Nuclear Factor Kappa B. Int. J. Mol. Sci. 2014, 15, 11957-11972. https://doi.org/10.3390/ijms150711957
Xiao WQ, Yin GJ, Fan YT, Qiu L, Cang XF, Yu G, Hu YL, Xing M, Wu DQ, Wang XP, et al. Catalpol Ameliorates Sodium Taurocholate-Induced Acute Pancreatitis in Rats via Inhibiting Activation of Nuclear Factor Kappa B. International Journal of Molecular Sciences. 2014; 15(7):11957-11972. https://doi.org/10.3390/ijms150711957
Chicago/Turabian StyleXiao, Wen Qin, Guo Jian Yin, Yu Ting Fan, Lei Qiu, Xiao Feng Cang, Ge Yu, Yan Ling Hu, Miao Xing, De Qing Wu, Xing Peng Wang, and et al. 2014. "Catalpol Ameliorates Sodium Taurocholate-Induced Acute Pancreatitis in Rats via Inhibiting Activation of Nuclear Factor Kappa B" International Journal of Molecular Sciences 15, no. 7: 11957-11972. https://doi.org/10.3390/ijms150711957