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Early Lung Cancer Diagnosis by Biosensors
Key Laboratory for Organic Electronics & Information Displays (KLOEID) and Institute of Advanced Materials (IAM), Nanjing University of Posts and Telecommunications, 9 Wenyuan Road, Nanjing 210023, China
College of Geography and Biological Information, Nanjing University of Posts and Telecommunications, 9 Wenyuan Road, Nanjing 210023, China
* Authors to whom correspondence should be addressed.
Received: 13 May 2013; in revised form: 29 June 2013 / Accepted: 4 July 2013 / Published: 25 July 2013
Abstract: Lung cancer causes an extreme threat to human health, and the mortality rate due to lung cancer has not decreased during the last decade. Prognosis or early diagnosis could help reduce the mortality rate. If microRNA and tumor-associated antigens (TAAs), as well as the corresponding autoantibodies, can be detected prior to clinical diagnosis, such high sensitivity of biosensors makes the early diagnosis and prognosis of cancer realizable. This review provides an overview of tumor-associated biomarker identifying methods and the biosensor technology available today. Laboratorial researches utilizing biosensors for early lung cancer diagnosis will be highlighted.
Keywords: lung cancer; early diagnosis; biomarker; microRNA; tumor-associated antigen; biosensor
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MDPI and ACS Style
Zhang, Y.; Yang, D.; Weng, L.; Wang, L. Early Lung Cancer Diagnosis by Biosensors. Int. J. Mol. Sci. 2013, 14, 15479-15509.
Zhang Y, Yang D, Weng L, Wang L. Early Lung Cancer Diagnosis by Biosensors. International Journal of Molecular Sciences. 2013; 14(8):15479-15509.
Zhang, Yuqian; Yang, Dongliang; Weng, Lixing; Wang, Lianhui. 2013. "Early Lung Cancer Diagnosis by Biosensors." Int. J. Mol. Sci. 14, no. 8: 15479-15509.