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Int. J. Mol. Sci. 2013, 14(12), 24064-24073; doi:10.3390/ijms141224064

Synthesis and Larvicidal Activity against Culex pipiens pallens of New Triazole Derivatives of Phrymarolin from Phryma leptostachya L.

1
College of Sciences, Northwest A&F University, Yangling 712100, China
2
Institute of Pesticide Science, Northwest A&F University, Yangling 712100, China
3
School of Life Science and Engineering, Southwest Jiaotong University, Chengdu 611756, China
*
Author to whom correspondence should be addressed.
Received: 28 October 2013 / Revised: 22 November 2013 / Accepted: 3 December 2013 / Published: 10 December 2013
(This article belongs to the Section Biochemistry, Molecular Biology and Biophysics)
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Abstract

Twelve new triazole derivatives of Phrymarolin were prepared from Phrymarolin I and the structures of all the derivatives were fully characterized by 1H-NMR, 13C-NMR and MS spectral data analyses. Larvicidal activities against 4rd instar larvae of Culex pipiens pallens of these Phrymarolin analogues were assayed. Although the triazole derivatives of Phrymarolin showed certain larvicidal activity, they showed lower activity than Phrymarolin I. The typical non-natural groups triazole substituents reduced the larvicidal activity of Phrymarolin derivatives. View Full-Text
Keywords: Phryma leptostachya L.; triazole; larvicidal activity; Culex pipiens pallens Phryma leptostachya L.; triazole; larvicidal activity; Culex pipiens pallens
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Zhang, J.-W.; Hu, Z.; Gao, P.; Wang, J.-R.; Hu, Z.-N.; Wu, W.-J. Synthesis and Larvicidal Activity against Culex pipiens pallens of New Triazole Derivatives of Phrymarolin from Phryma leptostachya L.. Int. J. Mol. Sci. 2013, 14, 24064-24073.

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