Int. J. Mol. Sci. 2013, 14(12), 24064-24073; doi:10.3390/ijms141224064
Article

Synthesis and Larvicidal Activity against Culex pipiens pallens of New Triazole Derivatives of Phrymarolin from Phryma leptostachya L.

1 College of Sciences, Northwest A&F University, Yangling 712100, China 2 Institute of Pesticide Science, Northwest A&F University, Yangling 712100, China 3 School of Life Science and Engineering, Southwest Jiaotong University, Chengdu 611756, China
* Author to whom correspondence should be addressed.
Received: 28 October 2013; in revised form: 22 November 2013 / Accepted: 3 December 2013 / Published: 10 December 2013
(This article belongs to the Section Bioactives and Nutraceuticals)
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Abstract: Twelve new triazole derivatives of Phrymarolin were prepared from Phrymarolin I and the structures of all the derivatives were fully characterized by 1H-NMR, 13C-NMR and MS spectral data analyses. Larvicidal activities against 4rd instar larvae of Culex pipiens pallens of these Phrymarolin analogues were assayed. Although the triazole derivatives of Phrymarolin showed certain larvicidal activity, they showed lower activity than Phrymarolin I. The typical non-natural groups triazole substituents reduced the larvicidal activity of Phrymarolin derivatives.
Keywords: Phryma leptostachya L.; triazole; larvicidal activity; Culex pipiens pallens

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MDPI and ACS Style

Zhang, J.-W.; Hu, Z.; Gao, P.; Wang, J.-R.; Hu, Z.-N.; Wu, W.-J. Synthesis and Larvicidal Activity against Culex pipiens pallens of New Triazole Derivatives of Phrymarolin from Phryma leptostachya L.. Int. J. Mol. Sci. 2013, 14, 24064-24073.

AMA Style

Zhang J-W, Hu Z, Gao P, Wang J-R, Hu Z-N, Wu W-J. Synthesis and Larvicidal Activity against Culex pipiens pallens of New Triazole Derivatives of Phrymarolin from Phryma leptostachya L.. International Journal of Molecular Sciences. 2013; 14(12):24064-24073.

Chicago/Turabian Style

Zhang, Ji-Wen; Hu, Zhan; Gao, Peng; Wang, Jun-Ru; Hu, Zhao-Nong; Wu, Wen-Jun. 2013. "Synthesis and Larvicidal Activity against Culex pipiens pallens of New Triazole Derivatives of Phrymarolin from Phryma leptostachya L.." Int. J. Mol. Sci. 14, no. 12: 24064-24073.

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