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Int. J. Mol. Sci. 2013, 14(11), 21781-21789; doi:10.3390/ijms141121781

Cladieunicellins K and L, New Eunicellin-Based Diterpenoids from an Octocoral Cladiella sp.

5,6,*  and 2,3,4,7,8,*
1 Department of Neurosurgery, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833, Taiwan 2 Graduate Institute of Marine Biotechnology, National Dong Hwa University, Pingtung 944, Taiwan 3 National Museum of Marine Biology and Aquarium, Pingtung 944, Taiwan 4 Department of Marine Biotechnology and Resources and Asia-Pacific Ocean Research Center, National Sun Yat-sen University, Kaohsiung 804, Taiwan 5 Department of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, China Medical University, Taichung 404, Taiwan 6 Department of Biotechnology, Asia University, Taichung 413, Taiwan 7 Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung 807, Taiwan 8 Chinese Medicine Research and Development Center, China Medical University Hospital, Taichung 404, Taiwan These authors contributed equally to this work.
* Authors to whom correspondence should be addressed.
Received: 8 October 2013 / Revised: 26 October 2013 / Accepted: 29 October 2013 / Published: 4 November 2013
(This article belongs to the Section Biochemistry, Molecular Biology and Biophysics)
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Two new eunicellin-based diterpenoids, cladieunicellins K (1) and L (2), were isolated from an octocoral Cladiella sp. The structures of 1 and 2 were elucidated by spectroscopic methods and 2 exhibited moderate cytotoxicity towards the MOLT-4 human leukemia.
Keywords: eunicellin; Cladiella; cladieunicellin; cytotoxicity eunicellin; Cladiella; cladieunicellin; cytotoxicity
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Shih, F.-Y.; Chen, T.-H.; Lu, M.-C.; Chen, W.-F.; Wen, Z.-H.; Kuo, Y.-H.; Sung, P.-J. Cladieunicellins K and L, New Eunicellin-Based Diterpenoids from an Octocoral Cladiella sp.. Int. J. Mol. Sci. 2013, 14, 21781-21789.

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