Int. J. Mol. Sci. 2013, 14(11), 21781-21789; doi:10.3390/ijms141121781
Article

Cladieunicellins K and L, New Eunicellin-Based Diterpenoids from an Octocoral Cladiella sp.

1,†email, 2,3,†email, 2,3email, 1,4email, 4email, 5,6,* email and 2,3,4,7,8,* email
1 Department of Neurosurgery, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833, Taiwan 2 Graduate Institute of Marine Biotechnology, National Dong Hwa University, Pingtung 944, Taiwan 3 National Museum of Marine Biology and Aquarium, Pingtung 944, Taiwan 4 Department of Marine Biotechnology and Resources and Asia-Pacific Ocean Research Center, National Sun Yat-sen University, Kaohsiung 804, Taiwan 5 Department of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, China Medical University, Taichung 404, Taiwan 6 Department of Biotechnology, Asia University, Taichung 413, Taiwan 7 Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung 807, Taiwan 8 Chinese Medicine Research and Development Center, China Medical University Hospital, Taichung 404, Taiwan These authors contributed equally to this work.
* Authors to whom correspondence should be addressed.
Received: 8 October 2013; in revised form: 26 October 2013 / Accepted: 29 October 2013 / Published: 4 November 2013
(This article belongs to the Section Bioactives and Nutraceuticals)
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Abstract: Two new eunicellin-based diterpenoids, cladieunicellins K (1) and L (2), were isolated from an octocoral Cladiella sp. The structures of 1 and 2 were elucidated by spectroscopic methods and 2 exhibited moderate cytotoxicity towards the MOLT-4 human leukemia.
Keywords: eunicellin; Cladiella; cladieunicellin; cytotoxicity

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MDPI and ACS Style

Shih, F.-Y.; Chen, T.-H.; Lu, M.-C.; Chen, W.-F.; Wen, Z.-H.; Kuo, Y.-H.; Sung, P.-J. Cladieunicellins K and L, New Eunicellin-Based Diterpenoids from an Octocoral Cladiella sp.. Int. J. Mol. Sci. 2013, 14, 21781-21789.

AMA Style

Shih F-Y, Chen T-H, Lu M-C, Chen W-F, Wen Z-H, Kuo Y-H, Sung P-J. Cladieunicellins K and L, New Eunicellin-Based Diterpenoids from an Octocoral Cladiella sp.. International Journal of Molecular Sciences. 2013; 14(11):21781-21789.

Chicago/Turabian Style

Shih, Fu-Yuan; Chen, Tsung-Hung; Lu, Mei-Chin; Chen, Wu-Fu; Wen, Zhi-Hong; Kuo, Yueh-Hsiung; Sung, Ping-Jyun. 2013. "Cladieunicellins K and L, New Eunicellin-Based Diterpenoids from an Octocoral Cladiella sp.." Int. J. Mol. Sci. 14, no. 11: 21781-21789.

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