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Cladieunicellins K and L, New Eunicellin-Based Diterpenoids from an Octocoral Cladiella sp.
Department of Neurosurgery, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833, Taiwan
Graduate Institute of Marine Biotechnology, National Dong Hwa University, Pingtung 944, Taiwan
National Museum of Marine Biology and Aquarium, Pingtung 944, Taiwan
Department of Marine Biotechnology and Resources and Asia-Pacific Ocean Research Center, National Sun Yat-sen University, Kaohsiung 804, Taiwan
Department of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, China Medical University, Taichung 404, Taiwan
Department of Biotechnology, Asia University, Taichung 413, Taiwan
Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung 807, Taiwan
Chinese Medicine Research and Development Center, China Medical University Hospital, Taichung 404, Taiwan
These authors contributed equally to this work.
* Authors to whom correspondence should be addressed.
Received: 8 October 2013; in revised form: 26 October 2013 / Accepted: 29 October 2013 / Published: 4 November 2013
Abstract: Two new eunicellin-based diterpenoids, cladieunicellins K (1) and L (2), were isolated from an octocoral Cladiella sp. The structures of 1 and 2 were elucidated by spectroscopic methods and 2 exhibited moderate cytotoxicity towards the MOLT-4 human leukemia.
Keywords: eunicellin; Cladiella; cladieunicellin; cytotoxicity
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Shih, F.-Y.; Chen, T.-H.; Lu, M.-C.; Chen, W.-F.; Wen, Z.-H.; Kuo, Y.-H.; Sung, P.-J. Cladieunicellins K and L, New Eunicellin-Based Diterpenoids from an Octocoral Cladiella sp.. Int. J. Mol. Sci. 2013, 14, 21781-21789.
Shih F-Y, Chen T-H, Lu M-C, Chen W-F, Wen Z-H, Kuo Y-H, Sung P-J. Cladieunicellins K and L, New Eunicellin-Based Diterpenoids from an Octocoral Cladiella sp.. International Journal of Molecular Sciences. 2013; 14(11):21781-21789.
Shih, Fu-Yuan; Chen, Tsung-Hung; Lu, Mei-Chin; Chen, Wu-Fu; Wen, Zhi-Hong; Kuo, Yueh-Hsiung; Sung, Ping-Jyun. 2013. "Cladieunicellins K and L, New Eunicellin-Based Diterpenoids from an Octocoral Cladiella sp.." Int. J. Mol. Sci. 14, no. 11: 21781-21789.