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In Vitro Antioxidant Activities of Sulfated Derivatives of Polysaccharides Extracted from Auricularia auricular
School of Food Science and Engineering, Harbin Institute of Technology, 73 HuangHe Road, NanGang District, Harbin 150090, China
School of Forestry, Northeast Forestry University, 26 HeXing Road, DongLi District, Harbin 150040, China
Symrise (Shanghai) Co., Ltd., Shanghai 201206, China
* Author to whom correspondence should be addressed.
Received: 28 March 2011; in revised form: 25 April 2011 / Accepted: 30 April 2011 / Published: 18 May 2011
Abstract: In this research, two types of sulfated polysaccharide derivatives were successfully synthesized. Their antioxidant activities were investigated by employing various established in vitro systems. In addition, the degree of sulfation was evaluated using ion-chromatography and IR spectra. The results verify that, when employing scavenging superoxide radical tests, both the sulfation of acid Auricularia auricular polysaccharides (SAAAP) and the sulfation of neutral Auricularia auricular polysaccharides (SNAAP) derivatives possessed considerable antioxidant activity and had a more powerful antioxidant competence than that of the native non-sulfated polysaccharides (AAAP and NAAP). On the other hand, AAAP and NAAP exhibited stronger activity on scavenging both the hydroxyl radical and lipid peroxidation. Available data obtained with in vitro measurements indicates that the sulfated groups of AAAP and NAAP played an important role on antioxidant activity. In sum, the research demonstrates that the antioxidant activity of sulfated polysaccharide derivatives in vitro has a potential significance for seeking new natural antioxidant protective agents.
Keywords: polysaccharides; Auricularia auricular; sulfated derivatives; antioxidant activities; in vitro
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MDPI and ACS Style
Zhang, H.; Wang, Z.-Y.; Yang, L.; Yang, X.; Wang, X.; Zhang, Z. In Vitro Antioxidant Activities of Sulfated Derivatives of Polysaccharides Extracted from Auricularia auricular. Int. J. Mol. Sci. 2011, 12, 3288-3302.
Zhang H, Wang Z-Y, Yang L, Yang X, Wang X, Zhang Z. In Vitro Antioxidant Activities of Sulfated Derivatives of Polysaccharides Extracted from Auricularia auricular. International Journal of Molecular Sciences. 2011; 12(5):3288-3302.
Zhang, Hua; Wang, Zhen-Yu; Yang, Lin; Yang, Xin; Wang, Xue; Zhang, Zhi. 2011. "In Vitro Antioxidant Activities of Sulfated Derivatives of Polysaccharides Extracted from Auricularia auricular." Int. J. Mol. Sci. 12, no. 5: 3288-3302.