Int. J. Mol. Sci. 2011, 12(2), 1133-1145; doi:10.3390/ijms12021133
Article

Expression and Clinical Role of Protein of Regenerating Liver (PRL) Phosphatases in Ovarian Carcinoma

Reuven Reich 1,* email, Shany Hadar 1 email and Ben Davidson 2,3,* email
1 Institute of Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 91120, Israel 2 Division of Pathology, Norwegian Radium Hospital, Oslo University Hospital, N-0310 Oslo, Norway 3 The Medical Faculty, University of Oslo, N-0316 Oslo, Norway
* Authors to whom correspondence should be addressed.
Received: 18 November 2010; in revised form: 26 January 2011 / Accepted: 7 February 2011 / Published: 11 February 2011
(This article belongs to the Special Issue Cancer Molecules in Ovarian Cancer)
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Abstract: The present study analyzed the expression and clinical role of the protein of regenerating liver (PRL) phosphatase family in ovarian carcinoma. PRL1-3 mRNA expression was studied in 184 tumors (100 effusions, 57 primary carcinomas, 27 solid metastases) using RT-PCR. PRL-3 protein expression was analyzed in 157 tumors by Western blotting. PRL-1 mRNA levels were significantly higher in effusions compared to solid tumors (p
Keywords: ovarian carcinoma; effusion; metastasis; PRL phosphatases; survival

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MDPI and ACS Style

Reich, R.; Hadar, S.; Davidson, B. Expression and Clinical Role of Protein of Regenerating Liver (PRL) Phosphatases in Ovarian Carcinoma. Int. J. Mol. Sci. 2011, 12, 1133-1145.

AMA Style

Reich R, Hadar S, Davidson B. Expression and Clinical Role of Protein of Regenerating Liver (PRL) Phosphatases in Ovarian Carcinoma. International Journal of Molecular Sciences. 2011; 12(2):1133-1145.

Chicago/Turabian Style

Reich, Reuven; Hadar, Shany; Davidson, Ben. 2011. "Expression and Clinical Role of Protein of Regenerating Liver (PRL) Phosphatases in Ovarian Carcinoma." Int. J. Mol. Sci. 12, no. 2: 1133-1145.

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