AbstractPhospholipase A1 (PLA1) is an enzyme that hydrolyzes phospholipids and produces 2-acyl-lysophospholipids and fatty acids. This lipolytic activity is conserved in a wide range of organisms but is carried out by a diverse set of PLA1 enzymes. Where their function is known, PLA1s have been shown to act as digestive enzymes, possess central roles in membrane maintenance and remodeling, or regulate important cellular mechanisms by the production of various lysophospholipid mediators, such as lysophosphatidylserine and lysophosphatidic acid, which in turn have multiple biological functions. View Full-Text
Share & Cite This Article
Richmond, G.S.; Smith, T.K. Phospholipases A1. Int. J. Mol. Sci. 2011, 12, 588-612.
Richmond GS, Smith TK. Phospholipases A1. International Journal of Molecular Sciences. 2011; 12(1):588-612.Chicago/Turabian Style
Richmond, Gregory S.; Smith, Terry K. 2011. "Phospholipases A1." Int. J. Mol. Sci. 12, no. 1: 588-612.