Next Article in Journal
QSAR Studies on Andrographolide Derivatives as α-Glucosidase Inhibitors
Next Article in Special Issue
Fructose Production by Inulinase Covalently Immobilized on Sepabeads in Batch and Fluidized Bed Bioreactor
Previous Article in Journal
Managing Phenol Contents in Crop Plants by Phytochemical Farming and Breeding—Visions and Constraints
Previous Article in Special Issue
Covalent Anchoring of Chloroperoxidase and Glucose Oxidase on the Mesoporous Molecular Sieve SBA-15
Article Menu

Export Article

Open AccessReview
Int. J. Mol. Sci. 2010, 11(3), 858-879; doi:10.3390/ijms11030858

Miniaturization in Biocatalysis

IBB–Institute for Biotechnology and Bioengineering, Centre for Biological and Chemical Engineering, Instituto Superior Técnico, Av. Rovisco Pais, 1049-001, Lisboa, Portugal
Received: 7 January 2010 / Revised: 8 February 2010 / Accepted: 9 February 2010 / Published: 2 March 2010
(This article belongs to the Special Issue Biocatalysis)
View Full-Text   |   Download PDF [218 KB, uploaded 19 June 2014]   |  

Abstract

The use of biocatalysts for the production of both consumer goods and building blocks for chemical synthesis is consistently gaining relevance. A significant contribution for recent advances towards further implementation of enzymes and whole cells is related to the developments in miniature reactor technology and insights into flow behavior. Due to the high level of parallelization and reduced requirements of chemicals, intensive screening of biocatalysts and process variables has become more feasible and reproducibility of the bioconversion processes has been substantially improved. The present work aims to provide an overview of the applications of miniaturized reactors in bioconversion processes, considering multi-well plates and microfluidic devices, update information on the engineering characterization of the hardware used, and present perspective developments in this area of research.
Keywords: multi-well plates; microreactors; enzyme immobilization; flow reactors; fluidic properties multi-well plates; microreactors; enzyme immobilization; flow reactors; fluidic properties
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Fernandes, P. Miniaturization in Biocatalysis. Int. J. Mol. Sci. 2010, 11, 858-879.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top