Int. J. Mol. Sci. 2010, 11(10), 3760-3768; doi:10.3390/ijms11103760
Article

The Individual and Combined Effects of Deoxynivalenol and Aflatoxin B1 on Primary Hepatocytes of Cyprinus Carpio

1 College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China 2 Wujiang agricultural commission, Wujiang, 215200, China
* Author to whom correspondence should be addressed.
Received: 26 August 2010; in revised form: 9 September 2010 / Accepted: 16 September 2010 / Published: 29 September 2010
(This article belongs to the Special Issue Advances in Molecular Toxicology)
PDF Full-text Download PDF Full-Text [370 KB, uploaded 29 September 2010 14:16 CEST]
Abstract: Aflatoxin B1 (AFB1) and deoxynivalenol (DON) are important food-borne mycotoxins that have been implicated in animal and human health. In this study, individual and combinative effects of AFB1 and DON were tested in primary hepatocytes of Cyprinus carpio. The results indicated that the combinative effects of AFB1 and DON (0.01 μg/mL AFB1 and 0.25 μg/mL DON; 0.02 μg/mL AFB1 and 0.25 μg/mL DON; 0.02 μg/mL AFB1 and 0.5 μg/mL DON) were higher than that of individual mycotoxin (P
Keywords: deoxynivalenol; aflatoxin B1; cytotoxicity; Cyprinus carpio; primary hepatocytes

Article Statistics

Load and display the download statistics.

Citations to this Article

Cite This Article

MDPI and ACS Style

He, C.-H.; Fan, Y.-H.; Wang, Y.; Huang, C.-Y.; Wang, X.-C.; Zhang, H.-B. The Individual and Combined Effects of Deoxynivalenol and Aflatoxin B1 on Primary Hepatocytes of Cyprinus Carpio. Int. J. Mol. Sci. 2010, 11, 3760-3768.

AMA Style

He C-H, Fan Y-H, Wang Y, Huang C-Y, Wang X-C, Zhang H-B. The Individual and Combined Effects of Deoxynivalenol and Aflatoxin B1 on Primary Hepatocytes of Cyprinus Carpio. International Journal of Molecular Sciences. 2010; 11(10):3760-3768.

Chicago/Turabian Style

He, Cheng-Hua; Fan, Yan-Hong; Wang, Ying; Huang, Chao-Ying; Wang, Xi-Chun; Zhang, Hai-Bin. 2010. "The Individual and Combined Effects of Deoxynivalenol and Aflatoxin B1 on Primary Hepatocytes of Cyprinus Carpio." Int. J. Mol. Sci. 11, no. 10: 3760-3768.

Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert