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Int. J. Mol. Sci. 2010, 11(10), 3760-3768; doi:10.3390/ijms11103760
Article

The Individual and Combined Effects of Deoxynivalenol and Aflatoxin B1 on Primary Hepatocytes of Cyprinus Carpio

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Received: 26 August 2010; in revised form: 9 September 2010 / Accepted: 16 September 2010 / Published: 29 September 2010
(This article belongs to the Special Issue Advances in Molecular Toxicology)
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Abstract: Aflatoxin B1 (AFB1) and deoxynivalenol (DON) are important food-borne mycotoxins that have been implicated in animal and human health. In this study, individual and combinative effects of AFB1 and DON were tested in primary hepatocytes of Cyprinus carpio. The results indicated that the combinative effects of AFB1 and DON (0.01 μg/mL AFB1 and 0.25 μg/mL DON; 0.02 μg/mL AFB1 and 0.25 μg/mL DON; 0.02 μg/mL AFB1 and 0.5 μg/mL DON) were higher than that of individual mycotoxin (P
Keywords: deoxynivalenol; aflatoxin B1; cytotoxicity; Cyprinus carpio; primary hepatocytes deoxynivalenol; aflatoxin B1; cytotoxicity; Cyprinus carpio; primary hepatocytes
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

He, C.-H.; Fan, Y.-H.; Wang, Y.; Huang, C.-Y.; Wang, X.-C.; Zhang, H.-B. The Individual and Combined Effects of Deoxynivalenol and Aflatoxin B1 on Primary Hepatocytes of Cyprinus Carpio. Int. J. Mol. Sci. 2010, 11, 3760-3768.

AMA Style

He C-H, Fan Y-H, Wang Y, Huang C-Y, Wang X-C, Zhang H-B. The Individual and Combined Effects of Deoxynivalenol and Aflatoxin B1 on Primary Hepatocytes of Cyprinus Carpio. International Journal of Molecular Sciences. 2010; 11(10):3760-3768.

Chicago/Turabian Style

He, Cheng-Hua; Fan, Yan-Hong; Wang, Ying; Huang, Chao-Ying; Wang, Xi-Chun; Zhang, Hai-Bin. 2010. "The Individual and Combined Effects of Deoxynivalenol and Aflatoxin B1 on Primary Hepatocytes of Cyprinus Carpio." Int. J. Mol. Sci. 11, no. 10: 3760-3768.


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