Next Article in Journal
Reactive Oxygen Species Enhance TLR10 Expression in the Human Monocytic Cell Line THP-1
Next Article in Special Issue
Comparison of TNFα to Lipopolysaccharide as an Inflammagen to Characterize the Idiosyncratic Hepatotoxicity Potential of Drugs: Trovafloxacin as an Example
Previous Article in Journal
Lewis Y Promotes Growth and Adhesion of Ovarian Carcinoma-Derived RMG-I Cells by Upregulating Growth Factors
Previous Article in Special Issue
Practical Application of Toxicogenomics for Profiling Toxicant-Induced Biological Perturbations
Int. J. Mol. Sci. 2010, 11(10), 3760-3768; doi:10.3390/ijms11103760
Article

The Individual and Combined Effects of Deoxynivalenol and Aflatoxin B1 on Primary Hepatocytes of Cyprinus Carpio

1
, 2
, 1
, 1
, 1
 and 1,*
Received: 26 August 2010; in revised form: 9 September 2010 / Accepted: 16 September 2010 / Published: 29 September 2010
(This article belongs to the Special Issue Advances in Molecular Toxicology)
View Full-Text   |   Download PDF [370 KB, uploaded 19 June 2014]   |   Browse Figures
Abstract: Aflatoxin B1 (AFB1) and deoxynivalenol (DON) are important food-borne mycotoxins that have been implicated in animal and human health. In this study, individual and combinative effects of AFB1 and DON were tested in primary hepatocytes of Cyprinus carpio. The results indicated that the combinative effects of AFB1 and DON (0.01 μg/mL AFB1 and 0.25 μg/mL DON; 0.02 μg/mL AFB1 and 0.25 μg/mL DON; 0.02 μg/mL AFB1 and 0.5 μg/mL DON) were higher than that of individual mycotoxin (P
Keywords: deoxynivalenol; aflatoxin B1; cytotoxicity; Cyprinus carpio; primary hepatocytes deoxynivalenol; aflatoxin B1; cytotoxicity; Cyprinus carpio; primary hepatocytes
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Export to BibTeX |
EndNote


MDPI and ACS Style

He, C.-H.; Fan, Y.-H.; Wang, Y.; Huang, C.-Y.; Wang, X.-C.; Zhang, H.-B. The Individual and Combined Effects of Deoxynivalenol and Aflatoxin B1 on Primary Hepatocytes of Cyprinus Carpio. Int. J. Mol. Sci. 2010, 11, 3760-3768.

AMA Style

He C-H, Fan Y-H, Wang Y, Huang C-Y, Wang X-C, Zhang H-B. The Individual and Combined Effects of Deoxynivalenol and Aflatoxin B1 on Primary Hepatocytes of Cyprinus Carpio. International Journal of Molecular Sciences. 2010; 11(10):3760-3768.

Chicago/Turabian Style

He, Cheng-Hua; Fan, Yan-Hong; Wang, Ying; Huang, Chao-Ying; Wang, Xi-Chun; Zhang, Hai-Bin. 2010. "The Individual and Combined Effects of Deoxynivalenol and Aflatoxin B1 on Primary Hepatocytes of Cyprinus Carpio." Int. J. Mol. Sci. 11, no. 10: 3760-3768.


Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert