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Int. J. Mol. Sci. 2009, 10(8), 3517-3530; doi:10.3390/ijms10083517
Review

Antihypertensive Properties of Plant-Based Prebiotics

,
,
 and *
School of Industrial Technology, Universiti Sains Malaysia, 11800 Penang, Malaysia
* Author to whom correspondence should be addressed.
Received: 25 June 2009 / Revised: 14 July 2009 / Accepted: 28 July 2009 / Published: 10 August 2009
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Abstract

Hypertension is one of the major risk factors for cardiovascular disease. Although various drugs for its treatment have been synthesized, the occurring side effects have generated the need for natural interventions for the treatment and prevention of hypertension. Dietary intervention such as the administration of prebiotics has been seen as a highly acceptable approach. Prebiotics are indigestible food ingredients that bypass digestion and reach the lower gut as substrates for indigenous microflora. Most of the prebiotics used as food adjuncts, such as inulin, fructooligosaccharides, dietary fiber and gums, are derived from plants. Experimental evidence from recent studies has suggested that prebiotics are capable of reducing and preventing hypertension. This paper will discuss some of the mechanisms involved, the evidence generated from both in-vitro experiments and in-vivo trials and some controversial findings that are raised.
Keywords: prebiotics; mechanism; evidence; controversies; inulin; fos; fiber; gum prebiotics; mechanism; evidence; controversies; inulin; fos; fiber; gum
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Yeo, S.-K.; Ooi, L.-G.; Lim, T.-J.; Liong, M.-T. Antihypertensive Properties of Plant-Based Prebiotics. Int. J. Mol. Sci. 2009, 10, 3517-3530.

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