Biodegradable Polydepsipeptides

doi:10.3390/ijms10020589

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Int. J. Mol. Sci. 2009, 10(2), 589-615; doi:10.3390/ijms10020589

Review

Biodegradable Polydepsipeptides

Yakai Feng * and Jintang Guo *

School of Chemical Engineering and Technology, Tianjin University / Weijin Road 92, 300072 Tianjin, P.R. China

* Authors to whom correspondence should be addressed.

Received: 5 January 2009; in revised form: 10 February 2009 / Accepted: 13 February 2009 / Published: 13 February 2009

(This article belongs to the Special Issue Biodegradability of Materials)

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Abstract: This paper reviews the synthesis, characterization, biodegradation and usage of bioresorbable polymers based on polydepsipeptides. The ring-opening polymerization of morpholine-2,5-dione derivatives using organic Sn and enzyme lipase is discussed. The dependence of the macroscopic properties of the block copolymers on their structure is also presented. Bioresorbable polymers based on polydepsipeptides could be used as biomaterials in drug controlled release, tissue engineering scaffolding and shape-memory materials.

Keywords: Polydepsipeptides; morpholine-2; 5-dione; biomaterials; biodegradation; ring-opening polymerization

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Cite This Article

MDPI and ACS Style

Feng, Y.; Guo, J. Biodegradable Polydepsipeptides. Int. J. Mol. Sci. 2009, 10, 589-615.

AMA Style

Feng Y., Guo J. Biodegradable Polydepsipeptides. International Journal of Molecular Sciences. 2009; 10(2):589-615.

Chicago/Turabian Style

Feng, Yakai; Guo, Jintang. 2009. "Biodegradable Polydepsipeptides." Int. J. Mol. Sci. 10, no. 2: 589-615.

Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI Publishing, Basel, Switzerland RSS E-Mail Table of Contents Alert