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Molecules 2004, 9(7), 527-534; doi:10.3390/90700527
Article

One Step Regioselective Synthesis of 5-Aminoisoxazoles from Nitrile Oxides and α-Cyanoenamines

1,* , 2 and 1
Received: 26 February 2004; Accepted: 5 April 2004 / Published: 30 June 2004
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Abstract: The 1,3-dipolar cycloaddition of nitrile oxides to 1-cyanoenamines gives 5-aminoisoxazoles regioselectively. Moderate to good yields could be obtained depending on the method used to generate the nitrile oxides. The intermediate isoxazolines could not be isolated.
Keywords: 1-Cyanoenamines; nitrile oxides; 1; 3-dipolar cycloaddition; 5-amino- isoxazoles. 1-Cyanoenamines; nitrile oxides; 1; 3-dipolar cycloaddition; 5-amino- isoxazoles.
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MDPI and ACS Style

Saad, A.; Vaultier, M.; Derdour, A. One Step Regioselective Synthesis of 5-Aminoisoxazoles from Nitrile Oxides and α-Cyanoenamines. Molecules 2004, 9, 527-534.

AMA Style

Saad A, Vaultier M, Derdour A. One Step Regioselective Synthesis of 5-Aminoisoxazoles from Nitrile Oxides and α-Cyanoenamines. Molecules. 2004; 9(7):527-534.

Chicago/Turabian Style

Saad, Amar; Vaultier, Michel; Derdour, Aïcha. 2004. "One Step Regioselective Synthesis of 5-Aminoisoxazoles from Nitrile Oxides and α-Cyanoenamines." Molecules 9, no. 7: 527-534.



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