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Molecules 2004, 9(7), 535-540; doi:10.3390/90700535

Formation of the Imidazolinone Ring Under Mild Conditions in the Presence of Sodium Hydride

Center for Chemical Research and Technologies, Cordoba Faculty, National Technological University, C.C. 17, Suc. 16, Cordoba 5016, Argentina
Author to whom correspondence should be addressed.
Received: 11 December 2003 / Revised: 15 September 2004 / Accepted: 19 September 2004 / Published: 30 June 2004
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Substituted imidazolinones containing heterocyclic carboxylic acids as substituents and possessing herbicidal properties were synthesized by cyclization of 2-amino-2,3-dimethylbutyramide with heterocyclic ethyl dicarboxylates under mild conditions. The use of NaH as base leads to a significant increase in the reaction rate and allows the preparation of the target compounds in high yields. View Full-Text
Keywords: Imidazolinones; herbicides; cyclization; sodium hydride Imidazolinones; herbicides; cyclization; sodium hydride

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This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Vasiliev, A.N.; Lopez, A.F.; Fernandez, J.D.; Mocchi, A.J. Formation of the Imidazolinone Ring Under Mild Conditions in the Presence of Sodium Hydride. Molecules 2004, 9, 535-540.

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