Regioselective Protection of the 4-Hydroxyl of 3,4-Dihydroxy-benzaldehyde

doi:10.3390/70900697

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Molecules 2002, 7(9), 697-705; doi:10.3390/70900697

Article

Regioselective Protection of the 4-Hydroxyl of 3,4-Dihydroxy-benzaldehyde

Guy L. Plourde* and Randy R. Spaetzel

University of Northern British Columbia, Department of Chemistry, 3333 University Way, Prince George, British Columbia, Canada

* Author to whom correspondence should be addressed.

Received: 30 July 2002; in revised form: 12 September 2002 / Accepted: 14 September 2002 / Published: 30 September 2003

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Abstract: The regioselective protection of the 4-hydroxyl group of 3,4-dihydroxy-benzaldehyde was accomplished with seven different protecting groups (benzyl, p-methoxybenzyl, o-nitrobenzyl, 2,6-dichlorobenzyl, 3,4-dichlorobenzyl, vinyl and propargyl) in yields ranging between 67-75%.

Keywords: regioselective; protection; catechol; 3; 4-dihydroxybenzaldehyde Introduction

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MDPI and ACS Style

Plourde, G.L.; Spaetzel, R.R. Regioselective Protection of the 4-Hydroxyl of 3,4-Dihydroxy-benzaldehyde. Molecules 2002, 7, 697-705.

AMA Style

Plourde GL, Spaetzel RR. Regioselective Protection of the 4-Hydroxyl of 3,4-Dihydroxy-benzaldehyde. Molecules. 2002; 7(9):697-705.

Chicago/Turabian Style

Plourde, Guy L.; Spaetzel, Randy R. 2002. "Regioselective Protection of the 4-Hydroxyl of 3,4-Dihydroxy-benzaldehyde." Molecules 7, no. 9: 697-705.

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