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Molecules 2002, 7(4), 405-411; doi:10.3390/70400405
Article

Synthesis of Platinum Complexes from N-Benzyl-1,3-Propanediamine Derivatives, Potential Antineoplastic Agents

1,* , 1, 1, 2,3, 1 and 3
Received: 17 August 2001 / Revised: 8 April 2002 / Accepted: 30 April 2002 / Published: 30 April 2002
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Abstract

This work describes the synthesis of seven new platinum complexes having Nbenzyl 1,3-propanediamine derivatives as ligands. They were prepared by the reaction of K2[PtCl4] with the appropriate ligand in water. These complexes are analogs of cisplatin, and are potential antineoplastic agents.
Keywords: Platinum(II) complexes; N-benzyl 1; 3-propanediamine; anticancer agents Platinum(II) complexes; N-benzyl 1; 3-propanediamine; anticancer agents
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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De Almeida, M.V.; Fontes, A.P.S.; Berg, R.N.; César, E.T.; De Castro Antunes Felício, E.; De Souza Filho, J.D. Synthesis of Platinum Complexes from N-Benzyl-1,3-Propanediamine Derivatives, Potential Antineoplastic Agents. Molecules 2002, 7, 405-411.

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