Molecules 2002, 7(4), 405-411; doi:10.3390/70400405
Article

Synthesis of Platinum Complexes from N-Benzyl-1,3-Propanediamine Derivatives, Potential Antineoplastic Agents

Mauro Vieira De Almeida 1,* email, Ana Paula Soares Fontes 1 , Richard Nilton Berg 1 , Eloi Teixeira César 2,3 , Emanoel De Castro Antunes Felício 1  and José Dias De Souza Filho 3
1 Departamento de Química, Universidade Federal de Juiz de Fora, 36036-330, Juiz de Fora-MG, Brazil 2 Colégio de Aplicação João XXIII, Juiz de Fora-MG, Brazil 3 Departamento de Química, Universidade Federal de Minas Gerais, Belo Horizonte-MG, Brazil
* Author to whom correspondence should be addressed.
Received: 17 August 2001; in revised form: 8 April 2002 / Accepted: 30 April 2002 / Published: 30 April 2002
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Abstract: This work describes the synthesis of seven new platinum complexes having Nbenzyl 1,3-propanediamine derivatives as ligands. They were prepared by the reaction of K2[PtCl4] with the appropriate ligand in water. These complexes are analogs of cisplatin, and are potential antineoplastic agents.
Keywords: Platinum(II) complexes; N-benzyl 1; 3-propanediamine; anticancer agents

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Cite This Article

MDPI and ACS Style

De Almeida, M.V.; Fontes, A.P.S.; Berg, R.N.; César, E.T.; De Castro Antunes Felício, E.; De Souza Filho, J.D. Synthesis of Platinum Complexes from N-Benzyl-1,3-Propanediamine Derivatives, Potential Antineoplastic Agents. Molecules 2002, 7, 405-411.

AMA Style

De Almeida MV, Fontes APS, Berg RN, César ET, De Castro Antunes Felício E, De Souza Filho JD. Synthesis of Platinum Complexes from N-Benzyl-1,3-Propanediamine Derivatives, Potential Antineoplastic Agents. Molecules. 2002; 7(4):405-411.

Chicago/Turabian Style

De Almeida, Mauro V.; Fontes, Ana P.S.; Berg, Richard N.; César, Eloi T.; De Castro Antunes Felício, Emanoel; De Souza Filho, José D. 2002. "Synthesis of Platinum Complexes from N-Benzyl-1,3-Propanediamine Derivatives, Potential Antineoplastic Agents." Molecules 7, no. 4: 405-411.

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