Molecules 2002, 7(2), 124-128; doi:10.3390/70200124
Article

Synthesis of 5,6-Dihydropyridin-2(1H)-ones, 1,5,6,8,8a-Hexahydroisoquinolin-3(2H)-ones and 4a,5,6,7,8,8a-Hexahydroquinolin-2(1H)-ones by Intramolecular Wittig Reaction

Department of Organic Chemistry, Omsk State University, Omsk, 644077, Russian Federation
* Author to whom correspondence should be addressed.
Received: 7 May 2001; in revised form: 15 January 2002 / Accepted: 16 January 2002 / Published: 28 February 2002
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Abstract: A new, universal and diastereospecific method has been developed for the synthesis of 5,6-dihydropyridin-2(1H)-ones, 1,5,6,8,8a-hexahydroisoquinolin-3(2H)-ones and 4a,5,6,7,8,8ahexahydroquinolin-2(1H)-ones (4) based on the intramolecular Wittig cyclization of the triphenyphosphonium salts 2 derived from the N-(3-oxoalkyl)–chloroacetamides 1.
Keywords: 5; 6-dihydropyridin-2(1H)-one; Wittig reaction; intramolecular cyclization; N-(3- oxoalkyl)chloroacetamide

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MDPI and ACS Style

Fisyuk, A.S.; Poendaev, N.V. Synthesis of 5,6-Dihydropyridin-2(1H)-ones, 1,5,6,8,8a-Hexahydroisoquinolin-3(2H)-ones and 4a,5,6,7,8,8a-Hexahydroquinolin-2(1H)-ones by Intramolecular Wittig Reaction. Molecules 2002, 7, 124-128.

AMA Style

Fisyuk AS, Poendaev NV. Synthesis of 5,6-Dihydropyridin-2(1H)-ones, 1,5,6,8,8a-Hexahydroisoquinolin-3(2H)-ones and 4a,5,6,7,8,8a-Hexahydroquinolin-2(1H)-ones by Intramolecular Wittig Reaction. Molecules. 2002; 7(2):124-128.

Chicago/Turabian Style

Fisyuk, Alexander S.; Poendaev, Nikolai V. 2002. "Synthesis of 5,6-Dihydropyridin-2(1H)-ones, 1,5,6,8,8a-Hexahydroisoquinolin-3(2H)-ones and 4a,5,6,7,8,8a-Hexahydroquinolin-2(1H)-ones by Intramolecular Wittig Reaction." Molecules 7, no. 2: 124-128.

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