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Molecules 2001, 6(9), 716-720; doi:10.3390/60900716
Article

Synthesis of Camalexin

1,* , 1
,
1
,
1 and 2
1 Department of Organic Chemistry, Faculty of Natural Sciences, P.J. Šafárik University, Moyzesova 11, 041 67 Košice, Slovak Republic 2 Institute of chemistry, Slovak Academy of Sciences, Dúbravská cesta 9, 842 38 Bratislava, Slovak Republic
* Author to whom correspondence should be addressed.
Received: 6 April 2001 / Revised: 13 August 2001 / Accepted: 14 August 2001 / Published: 31 August 2001
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Abstract

In this paper we describe a new method for the synthesis of camalexin (1) based on the reaction of 1-(tert-butoxycarbonyl)indole-3-carboxaldehyde with methyl Lcysteinate hydrochloride, followed by oxidation and decarboxylation. Compounds 1, and intermediates 5-7 were identified by elemental analysis, 1H NMR, 13C NMR and mass spectroscopy.
Keywords: Camalexin; phytoalexins; indoles Camalexin; phytoalexins; indoles
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Dzurilla, M.; Kutschy, P.; Zaletova, J.; Ruzinsky, M.; Kovacik, V. Synthesis of Camalexin. Molecules 2001, 6, 716-720.

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