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Molecules 2001, 6(9), 716-720; doi:10.3390/60900716

Synthesis of Camalexin

1,* , 1
1 and 2
1 Department of Organic Chemistry, Faculty of Natural Sciences, P.J. Šafárik University, Moyzesova 11, 041 67 Košice, Slovak Republic 2 Institute of chemistry, Slovak Academy of Sciences, Dúbravská cesta 9, 842 38 Bratislava, Slovak Republic
* Author to whom correspondence should be addressed.
Received: 6 April 2001 / Revised: 13 August 2001 / Accepted: 14 August 2001 / Published: 31 August 2001
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In this paper we describe a new method for the synthesis of camalexin (1) based on the reaction of 1-(tert-butoxycarbonyl)indole-3-carboxaldehyde with methyl Lcysteinate hydrochloride, followed by oxidation and decarboxylation. Compounds 1, and intermediates 5-7 were identified by elemental analysis, 1H NMR, 13C NMR and mass spectroscopy.
Keywords: Camalexin; phytoalexins; indoles Camalexin; phytoalexins; indoles
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Dzurilla, M.; Kutschy, P.; Zaletova, J.; Ruzinsky, M.; Kovacik, V. Synthesis of Camalexin. Molecules 2001, 6, 716-720.

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