Molecules 2001, 6(8), 710-715; doi:10.3390/60800710

Synthesis of 1-Benzyl-6-(4-chlorophenyl)-2-(4-R-phenyl)-4-(4-Rstyryl)-2,3-dihydropyrazolo[3,4-b][1,4]diazepines

1 Grupo de Investigación de Compuestos Heterocíclicos, Departamento de Química, Universidad del Valle, A.A. 25360, Cali, Colombia 2 Instituto de Química, UNAM, Circuito Exterior, C. Universitaria, Coyoacán, 04510, México, D. F. México 3 Laboratorio de Química Medicinal, Facultad de Estudios Superiores Cuautitlán, Universidad Nacional Autónoma de México, Cuautitlán, Estado de México, México
* Authors to whom correspondence should be addressed.
Received: 14 December 2000; in revised form: 20 July 2001 / Accepted: 26 July 2001 / Published: 31 July 2001
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Abstract: The reaction of 4-amino-5-benzylamino-3-(4-chlorophenyl)-1H-pyrazole (1) with substituted diarylidenketones (2) constitutes a convenient synthetic route to the hitherto unknown 1-benzyl-6-(4-chlorophenyl)-2-(4-R-phenyl)-4-(4-R-styryl)-2,3-dihydropyrazolo-[3,4-b][1,4]diazepines (3). Structures of all products were consistent with their IR, 1H-NMR, 13C-NMR and MS spectral data. X-ray crystallography data confirm the assigned structures.
Keywords: Diazepine derivatives; diarylidenketones

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MDPI and ACS Style

Insuasty, B.; Rodríguez, R.; Quiroga, J.; Abonía, R.; Martínez, R.; Toscano, A.; Angeles, E. Synthesis of 1-Benzyl-6-(4-chlorophenyl)-2-(4-R-phenyl)-4-(4-Rstyryl)-2,3-dihydropyrazolo[3,4-b][1,4]diazepines. Molecules 2001, 6, 710-715.

AMA Style

Insuasty B, Rodríguez R, Quiroga J, Abonía R, Martínez R, Toscano A, Angeles E. Synthesis of 1-Benzyl-6-(4-chlorophenyl)-2-(4-R-phenyl)-4-(4-Rstyryl)-2,3-dihydropyrazolo[3,4-b][1,4]diazepines. Molecules. 2001; 6(8):710-715.

Chicago/Turabian Style

Insuasty, Braulio; Rodríguez, Ricaurte; Quiroga, Jairo; Abonía, Rodrigo; Martínez, Roberto; Toscano, Alfredo; Angeles, E. 2001. "Synthesis of 1-Benzyl-6-(4-chlorophenyl)-2-(4-R-phenyl)-4-(4-Rstyryl)-2,3-dihydropyrazolo[3,4-b][1,4]diazepines." Molecules 6, no. 8: 710-715.

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