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Molecules 2001, 6(2), 130-141; doi:10.3390/60100130
Article

Natural Products From Sponges of the Genus Agelas - on the Trail of a [2+2]-Photoaddition Enzyme

1, 2, 1 and 1,*
Received: 4 July 2000; Accepted: 10 January 2001 / Published: 16 January 2001
(This article belongs to the Special Issue RACI Natural Products Group Symposium)
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Abstract: By specifically targeting sponges likely to contain oroidin derivatives, we have, for the first time, identified Australian sponges that contain sceptrin (2) and related compounds. Using a simple extraction technique and HPLC (with a photodiode array detector) in combination with LC-MS and MS-MS we have been able to quickly identify known compounds and flag the presence of some new compounds in the extracts. Further work will entail isolation and structure elucidation of the new compounds and collection of fresh Agelas sp.1 with the aim of isolating the enzyme that catalyses the [2 + 2] dimerisation or oroidin to sceptrin
Keywords: Agelas; sceptrin; sponge; [2+2] photoaddition Agelas; sceptrin; sponge; [2+2] photoaddition
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Hao, E.; Fromont, J.; Jardine, D.; Karuso, P. Natural Products From Sponges of the Genus Agelas - on the Trail of a [2+2]-Photoaddition Enzyme. Molecules 2001, 6, 130-141.

AMA Style

Hao E, Fromont J, Jardine D, Karuso P. Natural Products From Sponges of the Genus Agelas - on the Trail of a [2+2]-Photoaddition Enzyme. Molecules. 2001; 6(2):130-141.

Chicago/Turabian Style

Hao, Eleanor; Fromont, Jane; Jardine, Daniel; Karuso, Peter. 2001. "Natural Products From Sponges of the Genus Agelas - on the Trail of a [2+2]-Photoaddition Enzyme." Molecules 6, no. 2: 130-141.


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