Molecules 2001, 6(10), 815-824; doi:10.3390/61000815

Synthesis, Antibacterial and Antifungal Activity of 4-Substituted-5-Aryl-1,2,4-Triazoles

1, 1,* email, 2, 3 and 1
Received: 8 February 2001; in revised form: 24 September 2001 / Accepted: 26 September 2001 / Published: 30 September 2001
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: A few 4-allyl/amino-5-aryl-1,2,4-triazoles were synthesized and tested for antibacterial and antifungal effects against Escherichia coli, Bacillus subtilis, Salmonella enteritidis, Staphylococcus aureus, Aspergillus niger and Candida albicans. 4-Allyl-5-aryl-1,2,4-triazoles were obtained by the oxidative cyclization of the appropriate 1-substituted-4-allylthiosemicarbazides and 4-amino-5-aryl-1,2,4-triazoles were obtained by cyclization of the potassium salts of appropriately substituted dithiocarbazinic acids with hydrazine hydrate. The new synthesized compounds were characterized using IR, 1H- NMR, 13C-NMR and UV spectral data together with elemental analysis.
Keywords: Substituted benzoyl/phenylcetyl-4-allylthiosemicarbazides; 1; 2; 4-triazoles; cyclization; inhibition zone
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MDPI and ACS Style

Colanceska-Ragenovic, K.; Dimova, V.; Kakurinov, V.; Molnar, D.G.; Buzarovska, A. Synthesis, Antibacterial and Antifungal Activity of 4-Substituted-5-Aryl-1,2,4-Triazoles. Molecules 2001, 6, 815-824.

AMA Style

Colanceska-Ragenovic K, Dimova V, Kakurinov V, Molnar DG, Buzarovska A. Synthesis, Antibacterial and Antifungal Activity of 4-Substituted-5-Aryl-1,2,4-Triazoles. Molecules. 2001; 6(10):815-824.

Chicago/Turabian Style

Colanceska-Ragenovic, Katica; Dimova, Vesna; Kakurinov, Vlado; Molnar, Dora G.; Buzarovska, Aleksandra. 2001. "Synthesis, Antibacterial and Antifungal Activity of 4-Substituted-5-Aryl-1,2,4-Triazoles." Molecules 6, no. 10: 815-824.

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