Behaviour of Some Activated Nitriles Toward Barbituric Acid, Thiobarbituric Acid and 3-Methyl-1-Phenylpyrazol-5-one

doi:10.3390/50500746

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Molecules 2000, 5(5), 746-755; doi:10.3390/50500746

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Behaviour of Some Activated Nitriles Toward Barbituric Acid, Thiobarbituric Acid and 3-Methyl-1-Phenylpyrazol-5-one

H. M. Madkour * , M. R. Mahmoud, M. H. Nassar and M. M. Habashy

Synthetic Organic Chemistry Laboratory, Department of Chemistry, Faculty of Science, Ain Shams University, Abbassiya, Cairo, Egypt

* Author to whom correspondence should be addressed.

Received: 6 September 1999; in revised form: 15 December 1999 / Accepted: 12 February 2000 / Published: 20 May 2000

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Abstract: The effect of some active methylene containing heterocyclic compounds, namely barbituric acid, thiobarbituric acid and 3-methyl-1-phenylpyrazol-5-one on a-cyano-3,4,5-trimethoxycinnamonitrile and ethyl a-cyano-3,4,5-trimethoxycinnamate (1a,b) was investigated. The structure of the new products was substantiated by their IR,¹H-NMR and mass spectra.

Keywords: Barbituric and thiobarbituric acids; pyrazolone; and activated nitriles

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MDPI and ACS Style

Madkour, H.M.; Mahmoud, M.R.; Nassar, M.H.; Habashy, M.M. Behaviour of Some Activated Nitriles Toward Barbituric Acid, Thiobarbituric Acid and 3-Methyl-1-Phenylpyrazol-5-one. Molecules 2000, 5, 746-755.

AMA Style

Madkour H.M., Mahmoud M.R., Nassar M.H., Habashy M.M. Behaviour of Some Activated Nitriles Toward Barbituric Acid, Thiobarbituric Acid and 3-Methyl-1-Phenylpyrazol-5-one. Molecules. 2000; 5(5):746-755.

Chicago/Turabian Style

Madkour, H. M.; Mahmoud, M. R.; Nassar, M. H.; Habashy, M. M. 2000. "Behaviour of Some Activated Nitriles Toward Barbituric Acid, Thiobarbituric Acid and 3-Methyl-1-Phenylpyrazol-5-one." Molecules 5, no. 5: 746-755.

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