A Short Review on Cardiotonic Steroids and Their Aminoguanidine Analogues

doi:10.3390/50100051

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Molecules 2000, 5(1), 51-81; doi:10.3390/50100051

Review

A Short Review on Cardiotonic Steroids and Their Aminoguanidine Analogues

Concepción P. Melero * , Manuel Medarde and Arturo San Feliciano

Departamento de Química Farmacéutica, Facultad de Farmacia, Campus Miguel de Unamuno, 37007 Salamanca, Spain

* Author to whom correspondence should be addressed.

Received: 14 November 1999 / Accepted: 9 December 1999 / Published: 21 January 2000

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Abstract: A short review on cardiotonic steroids and their analogues is presented. The natural, semisynthetic and synthetic derivatives, as well as their mechanism of action and structure-activity relationships are shown, with a special reference to aminoguanidine derivatives.

Keywords: Digitalis glycosides analogues; structure-activity relationships; inotropic activity; Na+; K+-ATPase; aminoguanidine analogues

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MDPI and ACS Style

Melero, C.P.; Medarde, M.; San Feliciano, A. A Short Review on Cardiotonic Steroids and Their Aminoguanidine Analogues. Molecules 2000, 5, 51-81.

AMA Style

Melero C.P., Medarde M., San Feliciano A. A Short Review on Cardiotonic Steroids and Their Aminoguanidine Analogues. Molecules. 2000; 5(1):51-81.

Chicago/Turabian Style

Melero, Concepción P.; Medarde, Manuel; San Feliciano, Arturo. 2000. "A Short Review on Cardiotonic Steroids and Their Aminoguanidine Analogues." Molecules 5, no. 1: 51-81.

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