Molecules 2000, 5(1), 82-88; doi:10.3390/50100082
Article

A High-Yielding Synthesis of the Naturally Occurring Antitumour Agent Irisquinone

1 Cancer Research Campaign Section of Drug Development and Imaging, Paterson Institute for Cancer Research, Christie Hospital NHS Trust, Wilmslow Road, Manchester, M20 4BX, UK 2 Department of Biological Sciences, Salford University, Salford, M5 4WT, UK
* Author to whom correspondence should be addressed.
Received: 2 November 1999; Accepted: 12 January 2000 / Published: 18 January 2000
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Abstract: A short, high-yielding synthesis of the antitumour agent irisquinone (1) is described. The key steps are the palladium catalysed coupling reaction of dec-9-yn-1-ol with iodide (2) to form alkyne (3) and the Fremy’s salt oxidation of phenol (7).
Keywords: Irisquinone; antitumour; Chinese medicine

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MDPI and ACS Style

Hadfield, J.A.; McGown, A.T.; Butler, J. A High-Yielding Synthesis of the Naturally Occurring Antitumour Agent Irisquinone. Molecules 2000, 5, 82-88.

AMA Style

Hadfield JA, McGown AT, Butler J. A High-Yielding Synthesis of the Naturally Occurring Antitumour Agent Irisquinone. Molecules. 2000; 5(1):82-88.

Chicago/Turabian Style

Hadfield, John A.; McGown, Alan T.; Butler, John. 2000. "A High-Yielding Synthesis of the Naturally Occurring Antitumour Agent Irisquinone." Molecules 5, no. 1: 82-88.

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