Molecules 2000, 5(1), 82-88; doi:10.3390/50100082
Article

A High-Yielding Synthesis of the Naturally Occurring Antitumour Agent Irisquinone

1,* email, 1 and 2
Received: 2 November 1999; Accepted: 12 January 2000 / Published: 18 January 2000
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: A short, high-yielding synthesis of the antitumour agent irisquinone (1) is described. The key steps are the palladium catalysed coupling reaction of dec-9-yn-1-ol with iodide (2) to form alkyne (3) and the Fremy’s salt oxidation of phenol (7).
Keywords: Irisquinone; antitumour; Chinese medicine
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MDPI and ACS Style

Hadfield, J.A.; McGown, A.T.; Butler, J. A High-Yielding Synthesis of the Naturally Occurring Antitumour Agent Irisquinone. Molecules 2000, 5, 82-88.

AMA Style

Hadfield JA, McGown AT, Butler J. A High-Yielding Synthesis of the Naturally Occurring Antitumour Agent Irisquinone. Molecules. 2000; 5(1):82-88.

Chicago/Turabian Style

Hadfield, John A.; McGown, Alan T.; Butler, John. 2000. "A High-Yielding Synthesis of the Naturally Occurring Antitumour Agent Irisquinone." Molecules 5, no. 1: 82-88.

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