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Molecules 2000, 5(1), 51-81; doi:10.3390/50100051
Review

A Short Review on Cardiotonic Steroids and Their Aminoguanidine Analogues

* ,  and
Departamento de Química Farmacéutica, Facultad de Farmacia, Campus Miguel de Unamuno, 37007 Salamanca, Spain
* Author to whom correspondence should be addressed.
Received: 14 November 1999 / Accepted: 9 December 1999 / Published: 21 January 2000
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Abstract

A short review on cardiotonic steroids and their analogues is presented. The natural, semisynthetic and synthetic derivatives, as well as their mechanism of action and structure-activity relationships are shown, with a special reference to aminoguanidine derivatives.
Keywords: Digitalis glycosides analogues; structure-activity relationships; inotropic activity; Na+; K+-ATPase; aminoguanidine analogues Digitalis glycosides analogues; structure-activity relationships; inotropic activity; Na+; K+-ATPase; aminoguanidine analogues
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Melero, C.P.; Medarde, M.; San Feliciano, A. A Short Review on Cardiotonic Steroids and Their Aminoguanidine Analogues. Molecules 2000, 5, 51-81.

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