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Molecules 2018, 23(7), 1715; https://doi.org/10.3390/molecules23071715

Convenient Method of Synthesizing Aryloxyalkyl Esters from Phenolic Esters Using Halogenated Alcohols

1
Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China
2
Department of Pharmacy Administration & Clinical Pharmacy, Peking University, Beijing 100191, China
3
Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China
4
Key Laboratory of Biomedical Functional Materials, China Pharmaceutical University, Nanjing 210009, China
5
Food and Drug Research Institute, Jiangsu Food & Pharmaceutical Science College, Huaian 223003, China
*
Authors to whom correspondence should be addressed.
Received: 22 June 2018 / Revised: 10 July 2018 / Accepted: 12 July 2018 / Published: 13 July 2018
(This article belongs to the Section Organic Chemistry)
View Full-Text   |   Download PDF [3092 KB, uploaded 13 July 2018]   |  

Abstract

A facile one-pot synthetic method of building aryloxyalkyl esters was developed using various types of phenolic esters with halogenated alcohols. The ready availability of both starting materials, coupled with the required simple experimental technique, enables the current synthetic method of producing aryloxyalkyl esters in a fast and efficient way. It is noteworthy that acyl transfer was demonstrated in this reaction. View Full-Text
Keywords: aryloxyalkyl esters; phenolic esters; acyl transfer aryloxyalkyl esters; phenolic esters; acyl transfer
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Jiang, X.; Zhou, J.; Zhou, Y.; Sun, H.; Xu, J.; Feng, F.; Qu, W. Convenient Method of Synthesizing Aryloxyalkyl Esters from Phenolic Esters Using Halogenated Alcohols. Molecules 2018, 23, 1715.

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