A Tri-O-Bridged Diels-Alder Adduct from Cortex Mori Radicis
AbstractSanggenon X, an unusual tri-O-bridged Diels-Alder adduct, was isolated from Cortex Mori Radicis. Its structure was established by spectroscopic analysis, including NMR and HR-MS (High Resolution Mass Spectrometry). Sanggenon X contained three O-bridged rings, where the oxygenated bridgeheads were all quaternary carbons. Chemical methylation was carried out to deduce the linkages of the three O-bridges. The absolute configuration was determined by calculating the ECD (Electronic Circular Dichroism) using the TDDFT (Time-Dependent Density Functional Theory) method. Sanggenon X showed significant antioxidant activity against Fe2+-Cys-induced lipid peroxidation in rat liver microsomes, and was as effective as the positive control, curcumin. View Full-Text
- Supplementary File 1:
Supplementary (PDF, 2421 KB)
Scifeed alert for new publicationsNever miss any articles matching your research from any publisher
- Get alerts for new papers matching your research
- Find out the new papers from selected authors
- Updated daily for 49'000+ journals and 6000+ publishers
- Define your Scifeed now
Lu, A.-Q.; Chen, M.-H.; Gao, J.; Wang, L.; Yang, H.-Y.; Li, L.; Zhang, B.; He, H.-K.; Wang, S.-J. A Tri-O-Bridged Diels-Alder Adduct from Cortex Mori Radicis. Molecules 2018, 23, 133.
Lu A-Q, Chen M-H, Gao J, Wang L, Yang H-Y, Li L, Zhang B, He H-K, Wang S-J. A Tri-O-Bridged Diels-Alder Adduct from Cortex Mori Radicis. Molecules. 2018; 23(1):133.Chicago/Turabian Style
Lu, An-Qi; Chen, Ming-Hua; Gao, Jie; Wang, Lu; Yang, Han-Yu; Li, Lan; Zhang, Bo; He, Hao-Ke; Wang, Su-Juan. 2018. "A Tri-O-Bridged Diels-Alder Adduct from Cortex Mori Radicis." Molecules 23, no. 1: 133.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.