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Molecules 2017, 22(8), 1349; doi:10.3390/molecules22081349

Inositol Derivatives and Phenolic Compounds from the Roots of Taraxacum coreanum

College of Pharmacy, Chungbuk National University, Cheongju, Chungbuk 28160, Korea
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Received: 30 June 2017 / Revised: 13 August 2017 / Accepted: 13 August 2017 / Published: 14 August 2017
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Abstract

In this study, the characterization of chemical constituents and biological activity of the roots of Taraxacum coreanum (Asteraceae) was attempted. Phytochemical investigation of the roots of T. coreanum led to the isolation of two new inositol derivatives, taraxinositols A (1) and B (2), and a new phenolic compound, taraxinol (16), together with twenty known compounds including four inositol derivatives, neo-inositol-1,4-bis (4-hydroxybenzeneacetate) (3), chiro-inositol-1,5-bis(4- hydroxybenzeneacetate) (4), chiro-inositol-2,3-bis (4-hydroxybenzeneacetate) (5) and chiro-inositol- 1,2,3-tris (4-hydroxybenzeneacetate) (6), nine phenolic compounds: p-hydroxybenzaldehyde (7), vanillin (8), syringaldehyde (9), vanillic acid (10), 4-methoxyphenylacetic acid (11), 4-hydroxy- phenylacetic acid methyl ester (12), optivanin (13), isoferulic acid (14) and dihydroconiferyl alcohol (15), four coumarins: nodakenetin (17), decursinol (18), prangol (19) and isobyakangelicin (20), and three lignans: syringaresinol-4′-O-β-d-glucoside (21), syringaresinol (22), and pinoresinol (23). The structures of isolated compounds were determined on the basis of spectroscopic analysis. Among the isolated compounds, vanillic acid, isoferulic acid and syringaresinol showed radical scavenging activity with IC50 values ranging from 30.4 to 75.2 μM. View Full-Text
Keywords: Taraxacum coreanum; inositol; phenolic; antioxidant Taraxacum coreanum; inositol; phenolic; antioxidant
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MDPI and ACS Style

Mo, E.J.; Ahn, J.H.; Jo, Y.H.; Kim, S.B.; Hwang, B.Y.; Lee, M.K. Inositol Derivatives and Phenolic Compounds from the Roots of Taraxacum coreanum. Molecules 2017, 22, 1349.

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