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Molecules 2017, 22(8), 1279; doi:10.3390/molecules22081279

Effect of Sunlight Radiation on the Growth and Chemical Constituents of Salvia plebeia R.Br.

1
Immunoregulatory Material Research Center, Korea Research Institute of Bioscience and Biotechnology, 181 Ipsin-gil, Jeongeup-si, Jeonbuk 56212, Korea
2
Biological Resource Center, Korea Research Institute of Bioscience and Biotechnology, 181 Ipsin-gil, Jeongeup-si, Jeonbuk 56212, Korea
3
R&D Center, Korean Drug Co., Ltd., Seoul 06300, Korea
*
Authors to whom correspondence should be addressed.
Received: 10 July 2017 / Revised: 26 July 2017 / Accepted: 27 July 2017 / Published: 1 August 2017
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Abstract

This study investigated the chemical composition changes of Salvia plebeia R.Br. cultivated under different light sources, including florescent light and sunlight. The plants were exposed to fluorescent light for four months and sunlight and then examined for the next 5–7 months. Plants were harvested monthly during the seven months, and we examined whether the difference in light source affected the phenolic and flavonoid contents and antioxidant activity. A simple and reliable HPLC method using a PAH C18 column was applied for the quantitative analysis of two triterpenoids from the S. plebeia groups. Oleanolic acid (OA) and ursolic acid (UA) showed good linearity (R2 > 0.9999) within the test ranges (0.005–0.05 mg/mL), and the average percentage recoveries of the OA and UA were 95.1–104.8% and 97.2–107.1%, respectively. The intra- and inter-day relative standard deviations (RSDs) were less than 2.0%. After exposure to sunlight, the phenolic contents, including rosmarinic acid, showed a reduced tendency, whereas the flavonoid contents, including homoplantaginin and luteolin 7-glucoside, were increased. The content of the triterpenoids also showed an increased tendency under sunlight irradiation, but the variance was not larger than those of the phenolic and flavonoid contents. Among experimental groups, the group harvested at six months, having been exposed to sunlight for two months, showed the most potent antioxidant activity. Therefore, these results showed that the chemical composition and antioxidant activities of S. plebeia R.Br. was affected from environmental culture conditions, such as light source. Our studies will be useful for the development of functional materials using S. plebeia R.Br. View Full-Text
Keywords: Salvia plebeia; HPLC validation; triterpenoid; flavonoid; antioxidant; cultivation; UV Salvia plebeia; HPLC validation; triterpenoid; flavonoid; antioxidant; cultivation; UV
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Jang, H.-J.; Lee, S.-J.; Kim, C.Y.; Hwang, J.T.; Choi, J.H.; Park, J.H.; Lee, S.W.; Rho, M.-C. Effect of Sunlight Radiation on the Growth and Chemical Constituents of Salvia plebeia R.Br.. Molecules 2017, 22, 1279.

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