Anticancer and Immunogenic Properties of Cardiac Glycosides
AbstractCardiac glycosides (CGs) are natural compounds widely used in the treatment of several cardiac conditions and more recently have been recognized as potential antitumor compounds. They are known to be ligands for Na/K-ATPase, which is a promising drug target in cancer. More recently, in addition to their antitumor effects, it has been suggested that CGs activate tumor-specific immune responses. This review summarizes the anticancer aspects of CGs as new strategies for immunotherapy and drug repositioning (new horizons for old players), and the possible new targets for CGs in cancer cells. View Full-Text
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Schneider, N.F.Z.; Cerella, C.; Simões, C.M.O.; Diederich, M. Anticancer and Immunogenic Properties of Cardiac Glycosides. Molecules 2017, 22, 1932.
Schneider NFZ, Cerella C, Simões CMO, Diederich M. Anticancer and Immunogenic Properties of Cardiac Glycosides. Molecules. 2017; 22(11):1932.Chicago/Turabian Style
Schneider, Naira F.Z.; Cerella, Claudia; Simões, Cláudia Maria Oliveira; Diederich, Marc. 2017. "Anticancer and Immunogenic Properties of Cardiac Glycosides." Molecules 22, no. 11: 1932.
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