Next Article in Journal
Chemical Composition, Antioxidant, and Antibacterial Activity of Wood Vinegar from Litchi chinensis
Previous Article in Journal
Passerini Reactions on Biocatalytically Derived Chiral Azetidines
Article Menu
Issue 9 (September) cover image

Export Article

Open AccessArticle
Molecules 2016, 21(9), 1152; doi:10.3390/molecules21091152

Mexicanolide-Type Limonoids from the Roots of Trichilia sinensis

Tropical Crops Genetic Resources Institute, Chinese Academy of Tropical Agricultural Sciences, Danzhou 571737, China
Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China
Authors to whom correspondence should be addressed.
Academic Editor: Derek J. McPhee
Received: 8 August 2016 / Revised: 22 August 2016 / Accepted: 26 August 2016 / Published: 30 August 2016
View Full-Text   |   Download PDF [629 KB, uploaded 30 August 2016]   |  


Four new mexicanolide-type limonoids 14, along with two known limonoids 56, were isolated from the ethanolic extracts of roots of the Traditional Chinese Medicine Trichilia sinensis. Their structures were unambiguously determined by analysis of spectroscopic data, including 1D and 2D NMR as well as MS, and by comparison with literature data. In addition, the acetylcholinesterase (AChE) inhibitory activity of compounds 16 was evaluated by the Ellman method. All these compounds showed weak AChE inhibitory activity, with the inhibition percentages ranging from 18.5% to 27.8%. View Full-Text
Keywords: Trichilia sinensis; meliaceae; limonoids; mexicanolide-type; AChE inhibitory activity Trichilia sinensis; meliaceae; limonoids; mexicanolide-type; AChE inhibitory activity

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Supplementary material

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Liu, S.-B.; Mei, W.-L.; Chen, H.-Q.; Guo, Z.-K.; Dai, H.-F.; Wang, Z.-N. Mexicanolide-Type Limonoids from the Roots of Trichilia sinensis. Molecules 2016, 21, 1152.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top