Next Article in Journal
Rearrangements of Cycloalkenyl Aryl Ethers
Previous Article in Journal
Properties of the Sodium Naproxen-Lactose-Tetrahydrate Co-Crystal upon Processing and Storage
Article Menu
Issue 4 (April) cover image

Export Article

Open AccessArticle
Molecules 2016, 21(4), 513; doi:10.3390/molecules21040513

Comparison of Antioxidant Capability after Isopropanol Salting-Out Pretreatment and n-Butanol Partition Extraction, and Identification and Evaluation of Antioxidants of Sedum formosanum N.E.Br.

1
Department of Mechanical Engineering, Nan-Kai University of Technology, 568 ZhongZheng Road, Caotun, Nantou County 542, Taiwan
2
Department of Chemistry, National Chung Hsing University 250 Kuo-Kuang Road, Taichung 402, Taiwan
3
Department of Medical Research, Taichung Veterans General Hospital, 1650 Taiwan Road Sec, Taichung 402, Taiwan
These authors contributed equally to this work.
*
Authors to whom correspondence should be addressed.
Academic Editor: Maurizio Battino
Received: 16 February 2016 / Revised: 12 April 2016 / Accepted: 13 April 2016 / Published: 19 April 2016
(This article belongs to the Section Natural Products)
View Full-Text   |   Download PDF [1513 KB, uploaded 19 April 2016]   |  

Abstract

Crude extracts of Sedum formosanum N.E.Br. obtained from n-butanol partition (BP) and isopropanol salting-out pretreatment (ISP) were analyzed using antioxidation assays. The results indicated that the extract from ISP contained more potent antioxidants and thus exhibited more antioxidant activity in all the assays. The superoxide radical-scavenging activity and inhibition of nitric oxide radicals achieved after ISP were 3.65 and 2.18 times higher than those achieved through BP, respectively. Eight bioactive natural products were isolated and identified according to an analysis of antioxidation activity in different fractions of the ISP crude extract, namely three cyanophoric glycosides 13, three flavonoids 46 and two phenolic compounds (7 and a new compound 8). Among them, compounds 5 and 6 exhibit the highest antioxidation capability, and the ISP is suitable for obtaining compounds 5 and 6 using HPLC chromatograms. Therefore, ISP is an excellent extraction technology that can be used to extract antioxidant compounds in the nutraceutical and pharmaceutical industries. View Full-Text
Keywords: S. formosanum N.E.Br.; salting-out; cyanophoric glycoside; flavonoids; antioxidant activity S. formosanum N.E.Br.; salting-out; cyanophoric glycoside; flavonoids; antioxidant activity
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Chen, J.-H.; Lai, W.-H.; Lin, S.-D.; Lan, C.-F.; Hsu, S.-L.; Liao, M.-Y. Comparison of Antioxidant Capability after Isopropanol Salting-Out Pretreatment and n-Butanol Partition Extraction, and Identification and Evaluation of Antioxidants of Sedum formosanum N.E.Br.. Molecules 2016, 21, 513.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top