Next Article in Journal
Isolation, Purification and Quantification of Ginsenoside F5 and F3 Isomeric Compounds from Crude Extracts of Flower Buds of Panax ginseng
Next Article in Special Issue
Photophysical Characterization and in Vitro Phototoxicity Evaluation of 5,10,15,20-Tetra(quinolin-2-yl)porphyrin as a Potential Sensitizer for Photodynamic Therapy
Previous Article in Journal
Hydrazonoyl Chlorides as Precursors for Synthesis of Novel Bis-Pyrrole Derivatives
Previous Article in Special Issue
Porphyrins as Catalysts in Scalable Organic Reactions
Article Menu
Issue 3 (March) cover image

Export Article

Open AccessReview
Molecules 2016, 21(3), 320; doi:10.3390/molecules21030320

Porphyrin Macrocycle Modification: Pyrrole Ring-Contracted or -Expanded Porphyrinoids

Department of Chemistry and QOPNA, University of Aveiro, 3810-193 Aveiro, Portugal
Author to whom correspondence should be addressed.
Academic Editors: M. Graça P. M. S. Neves and M. Amparo F. Faustino
Received: 1 February 2016 / Revised: 24 February 2016 / Accepted: 1 March 2016 / Published: 9 March 2016


In recent years, several synthetic strategies aiming at the peripheral functionalization of porphyrins were developed. Particularly interesting are those involving the modification of β-pyrrolic positions leading to pyrrole-modified porphyrins containing four-, five-, six- or seven-membered heterocycles. Azeteoporphyrins, porpholactones and morpholinoporphyrins are representative examples of such porphyrinoids. These porphyrin derivatives have recently gained an increasing interest due to their potential application in PDT, as multimodal imaging contrast agents, NIR-absorbing dyes, optical sensors for oxygen, cyanide, hypochlorite and pH, and in catalysis. View Full-Text
Keywords: porphyrinoids; secochlorins; chlorophins; bacteriophins; azeteoporphyrins; porpholactones; pyriporphyrins; morpholinoporphyrins porphyrinoids; secochlorins; chlorophins; bacteriophins; azeteoporphyrins; porpholactones; pyriporphyrins; morpholinoporphyrins

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Costa, L.D.; Costa, J.I.; Tomé, A.C. Porphyrin Macrocycle Modification: Pyrrole Ring-Contracted or -Expanded Porphyrinoids. Molecules 2016, 21, 320.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top