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Molecules 2016, 21(2), 160; doi:10.3390/molecules21020160

Naphthalenones and Depsidones from a Sponge-Derived Strain of the Fungus Corynespora cassiicola

1
Key Laboratory of Marine Drugs, the Ministry of Education of China, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China
2
Institute of Evolution & Marine Biodiversity, Ocean University of China, Qingdao 266003, China
*
Author to whom correspondence should be addressed.
Academic Editor: Derek J. McPhee
Received: 15 December 2015 / Revised: 23 January 2016 / Accepted: 26 January 2016 / Published: 28 January 2016
(This article belongs to the Section Natural Products)
View Full-Text   |   Download PDF [457 KB, uploaded 28 January 2016]   |  

Abstract

Two new naphthalenones, corynenones A and B (1 and 2), and one new depsidone, corynesidone E (3), together with one known depsidone, corynesidone A (4) and two known diphenyl ethers, corynethers A (5) and B (6), were isolated from the sponge-derived fungus Corynespora cassiicola XS-20090I7. Their structures including absolute configurations were determined by spectroscopic data and electronic circular dichroism (ECD) spectra. Compounds 4 and 5 showed cytotoxicity against human promyelocytic leukemia HL-60 and human cervical carcinoma HeLa cell lines. View Full-Text
Keywords: sponge-derived fungus; Corynespora cassiicola; naphthalenone; depsidone; cytotoxicity sponge-derived fungus; Corynespora cassiicola; naphthalenone; depsidone; cytotoxicity
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Zhao, D.-L.; Shao, C.-L.; Wang, C.-Y.; Wang, M.; Yang, L.-J.; Wang, C.-Y. Naphthalenones and Depsidones from a Sponge-Derived Strain of the Fungus Corynespora cassiicola. Molecules 2016, 21, 160.

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