Terpenoids from the Marine-Derived Fungus Aspergillus fumigatus YK-7
AbstractTwo new β-bergamotane sesquiterpenoids, E-β-trans-5,8,11-trihydroxybergamot-9-ene (1) and β-trans-2β,5,15-trihydroxybergamot-10-ene (2), were isolated from the marine-derived fungus Aspergillus fumigatus YK-7, along with three known terpenoids 3–5. Their structures were determined by spectroscopic methods (1D and 2D NMR, HR-ESI-MS). Antiproliferative effects on human leukemic monocyte lymphoma U937 and human prostate cancer PC-3 cell lines were measured in vitro. Compound 4 exhibited potent activity against the U937 cell line with an IC50 value of 4.2 μM. View Full-Text
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Wang, Y.; Li, D.-H.; Li, Z.-L.; Sun, Y.-J.; Hua, H.-M.; Liu, T.; Bai, J. Terpenoids from the Marine-Derived Fungus Aspergillus fumigatus YK-7. Molecules 2016, 21, 31.
Wang Y, Li D-H, Li Z-L, Sun Y-J, Hua H-M, Liu T, Bai J. Terpenoids from the Marine-Derived Fungus Aspergillus fumigatus YK-7. Molecules. 2016; 21(1):31.Chicago/Turabian Style
Wang, Yu; Li, Da-Hong; Li, Zhan-Lin; Sun, Yan-Jun; Hua, Hui-Ming; Liu, Tao; Bai, Jiao. 2016. "Terpenoids from the Marine-Derived Fungus Aspergillus fumigatus YK-7." Molecules 21, no. 1: 31.
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