A New Bioactive Metabolite Isolated from the Red Sea Marine Sponge Hyrtios erectus
AbstractChemical investigation of the lipophilic fraction of Hyrtios erectus, a Red Sea sponge, yielded a new pentacyclic nitrogen-containing scalarane; 24-methoxypetrosaspongia C (1), together with the previously reported scalaranes sesterstatin 3 (2), 12-deacetyl-12-epi-scalaradial (3) and 12-deacetyl-12,18-di-epi-scalaradial (4). The compounds were identified using HRESIMS, 1D and 2D NMR experiments. The isolated compounds showed growth inhibitory activity against hepatocellular carcinoma (HepG2), colorectal carcinoma (HCT-116) and breast adenocarcinoma cells (MCF-7). View Full-Text
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Elhady, S.S.; El-Halawany, A.M.; Alahdal, A.M.; Hassanean, H.A.; Ahmed, S.A. A New Bioactive Metabolite Isolated from the Red Sea Marine Sponge Hyrtios erectus. Molecules 2016, 21, 82.
Elhady SS, El-Halawany AM, Alahdal AM, Hassanean HA, Ahmed SA. A New Bioactive Metabolite Isolated from the Red Sea Marine Sponge Hyrtios erectus. Molecules. 2016; 21(1):82.Chicago/Turabian Style
Elhady, Sameh S.; El-Halawany, Ali M.; Alahdal, Abdulrahman M.; Hassanean, Hashim A.; Ahmed, Safwat A. 2016. "A New Bioactive Metabolite Isolated from the Red Sea Marine Sponge Hyrtios erectus." Molecules 21, no. 1: 82.
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