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Molecules 2016, 21(1), 122; doi:10.3390/molecules21010122

Synthesis of Some Novel 2-Amino-5-arylazothiazole Disperse Dyes for Dyeing Polyester Fabrics and Their Antimicrobial Activity

Textile Research Division, National Research Center, Dokki, Giza, P. O. Box.12611, Egypt
Chemistry Department, College of Science, King Saud University, P. O. Box 2455, Riyadh 11451, Saudi Arabia
Chemistry Department, Faculty of Science, Taif University, P. O. Box 888, Taif 21974, Saudi Arabia
Department of Chemical Engineering, Higher Institute for Engineering and Technology, New Damietta, P. O. Box 34518, Egypt
These authors contributed equally to this work.
Author to whom correspondence should be addressed.
Academic Editor: Richard A. Bunce
Received: 20 December 2015 / Revised: 9 January 2016 / Accepted: 18 January 2016 / Published: 21 January 2016
(This article belongs to the Collection Heterocyclic Compounds)
View Full-Text   |   Download PDF [1430 KB, uploaded 21 January 2016]   |  


The present work describes the synthesis of a series of four novel biologically active 2-amino-5-arylazothiazole disperse dyes containing the sulfa drug nucleus. The structures of the synthesized thiazole derivatives are confirmed using UV-spectrophotometry, infrared and nuclear magnetic resonance techniques and elemental analysis. The synthesized dyes are applied to polyester fabrics as disperse dyes and their fastness properties to washing, perspiration, rubbing, sublimation, and light are evaluated. The synthesized compounds exhibit promising biological efficiency against selected Gram-positive and Gram-negative pathogenic bacteria as well as fungi. View Full-Text
Keywords: azo dyes; 2-aminothiazole; sulfaguanidine; polyester; dyeing; antimicrobial activity azo dyes; 2-aminothiazole; sulfaguanidine; polyester; dyeing; antimicrobial activity

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Gaffer, H.E.; Fouda, M.M.G.; Khalifa, M.E. Synthesis of Some Novel 2-Amino-5-arylazothiazole Disperse Dyes for Dyeing Polyester Fabrics and Their Antimicrobial Activity. Molecules 2016, 21, 122.

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