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Molecules 2015, 20(8), 13496-13517; doi:10.3390/molecules200813496

Recent Developments and Biological Activities of N-Substituted Carbazole Derivatives: A Review

Department of Pharmacy, Bahauddin Zakariya University, Multan 60800, Pakistan
These authors contributed equally to this work.
*
Author to whom correspondence should be addressed.
Academic Editor: Eugene Babaev
Received: 22 March 2015 / Revised: 9 June 2015 / Accepted: 24 June 2015 / Published: 23 July 2015
(This article belongs to the Collection Heterocyclic Compounds)

Abstract

Carbazoles represent an important class of heterocycles. These have been reported to exhibit diverse biological activities such as antimicrobial, antitumor, antiepileptic, antihistaminic, antioxidative, anti-inflammatory, antidiarrhoeal, analgesic, neuroprotective and pancreatic lipase inhibition properties. A series of carbazole derivatives such as N-substituted carbazoles, benzocarbazoles, furocarbazoles, pyrrolocarbazoles, indolocarbazoles, imidazocarbazoles, etc. have been synthesized. The N-substituted derivatives have gained the attention of researchers due to their therapeutic potential against neurological disorders and cell proliferation. Herein an attempt is made to review the medicinal importance of recently synthesized N-substituted carbazoles. View Full-Text
Keywords: N-substituted carbazoles; antimicrobial; anticancer; neuroprotective N-substituted carbazoles; antimicrobial; anticancer; neuroprotective
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Bashir, M.; Bano, A.; Ijaz, A.S.; Chaudhary, B.A. Recent Developments and Biological Activities of N-Substituted Carbazole Derivatives: A Review. Molecules 2015, 20, 13496-13517.

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