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Molecules 2015, 20(6), 11063-11075; doi:10.3390/molecules200611063

New Polyphenols Identified in Artemisiae abrotani herba Extract

1
Pharmaceutical Botany Department, Faculty of Pharmacy, Iuliu Hațieganu University of Medicine and Pharmacy, 23 Marinescu Street, Cluj-Napoca 400037, Romania
2
Pharmaceutical Technology and Biopharmaceutics Department, Faculty of Pharmacy, Iuliu Hațieganu University of Medicine and Pharmacy, 12 I. Creanga Street, Cluj-Napoca 400010, Romania
3
Physical Chemistry Department, Faculty of Pharmacy, Iuliu Hațieganu University of Medicine and Pharmacy, 6 Louis Pasteur Street, Cluj-Napoca 400349, Romania
*
Authors to whom correspondence should be addressed.
Academic Editor: Derek J. McPhee
Received: 2 May 2015 / Revised: 27 May 2015 / Accepted: 8 June 2015 / Published: 15 June 2015
(This article belongs to the Section Natural Products)
View Full-Text   |   Download PDF [785 KB, uploaded 15 June 2015]   |  

Abstract

Artemisia abrotanum L. (“southernwood”) belongs to the Artemisia genus and it is used in traditional medicine for the treatment of a variety of illnesses. Scarce data is available on the chemical composition of this medicinal plant, most research being focused on the quantitative and qualitative analyses of its essential oil. Our aim was to investigate the content and profile of polyphenols, flavonoids and hydroxycinnamic derivatives present in the Artemisiae abrotani herba extract. We conducted LC/MS analysis and we screened for 19 polyphenols, flavonoids and hydroxycinnamic derivatives. We determined the total content of these compounds and we screened for antioxidant activity. Most polyphenol acids, hydroxycinnamic derivatives and flavonoids were identified and quantified for the first time in this study. We found an original polyphenol distribution profile with high concentration of sinapic acid, rutin, quercetol, ferulic acid and patuletin. We measured the antioxidant activity, the ethanolic extract presenting a modest radical scavenging activity. The value of this study consists in its novelty as it adds new data on the chemical composition of A. abrotanum L. and it opens novel perspectives for medical and nutritional applications of this plant. View Full-Text
Keywords: Artemisia abrotanum L.; polyphenols; flavonoids; hydroxycinnamic derivatives; phenolic acids; natural antioxidants; bioactive compounds; healthy nutrition Artemisia abrotanum L.; polyphenols; flavonoids; hydroxycinnamic derivatives; phenolic acids; natural antioxidants; bioactive compounds; healthy nutrition
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Baiceanu, E.; Vlase, L.; Baiceanu, A.; Nanes, M.; Rusu, D.; Crisan, G. New Polyphenols Identified in Artemisiae abrotani herba Extract. Molecules 2015, 20, 11063-11075.

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