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Molecules 2015, 20(3), 4483-4491; doi:10.3390/molecules20034483

Two New Phenolic Glucosides from Lagerstroemia speciosa

1
College of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University, Seoul 151-742, Korea
2
Department of Genetic Engineering, Sungkyunkwan University, Suwon 440-746, Korea
3
College of Pharmacy, The Catholic University of Korea, Bucheon 420-743, Korea
4
Department of Life Science, Hallym University, Chuncheon 200-702, Korea
5
Popa mountain park, Forest Department, Kyaukpadaung Township, Mandalay Division, Myanmar
6
College of Pharmacy and RFIND-BKplus Team, Dongguk University-Seoul, 32 Dongguk-lo, Ilsan dong-gu, Goyang 410-820, Korea
7
Department of Forest Sciences, Seoul National University, Seoul 151-921, Korea
These authors contributed equally to this work.
*
Author to whom correspondence should be addressed.
Academic Editor: Derek J. McPhee
Received: 6 February 2015 / Revised: 4 March 2015 / Accepted: 5 March 2015 / Published: 10 March 2015
(This article belongs to the Section Natural Products)
View Full-Text   |   Download PDF [718 KB, uploaded 10 March 2015]   |  

Abstract

Two new phenolic glucosides, 1-O-benzyl-6-O-E-caffeoyl-β-d-glucopyranoside and 1-O-(7S,8R)-guaiacylglycerol-(6-O-E-caffeoyl)-β-d-glucopyranoside, were isolated from the aerial parts of Lagerstroemia speciosa, along with ten known compounds. The structures of the isolated compounds were determined based on 1D- and 2D-NMR, Q-TOF MS and optical rotation spectroscopic data. All of the compounds showed moderate inhibitory activities against nitric oxide production in lipopolysaccharide-treated RAW264.7 cells, with IC50 values of 69.5–83.3 μM. View Full-Text
Keywords: Lagerstroemia speciosa; phenolic glucoside; inhibitory activities against nitric oxide production Lagerstroemia speciosa; phenolic glucoside; inhibitory activities against nitric oxide production
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MDPI and ACS Style

Choi, J.; Cho, J.Y.; Choi, S.J.; Jeon, H.; Kim, Y.D.; Htwe, K.M.; Chin, Y.W.; Lee, W.S.; Kim, J.; Yoon, K.D. Two New Phenolic Glucosides from Lagerstroemia speciosa. Molecules 2015, 20, 4483-4491.

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