Inhibition of Glutamine Synthetase: A Potential Drug Target in Mycobacterium tuberculosis
Abstract
:1. Introduction
2. Inhibitors of GS
2.1. Amino Acid Analogues
2.2. Heterocycles
2.2.1. Purine Analogues as Novel ATP-Competitive Inhibitors
2.2.2. 3-Aminoimidazo[1,2-a]pyridines
2.2.3. 2,4,5-Trisubtituted Imidazoles
2.2.4. Potential ATP-Competitive Inhibitors
3. Conclusions
Acknowledgments
Author Contributions
Conflicts of Interest
References
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Mowbray, S.L.; Kathiravan, M.K.; Pandey, A.A.; Odell, L.R. Inhibition of Glutamine Synthetase: A Potential Drug Target in Mycobacterium tuberculosis. Molecules 2014, 19, 13161-13176. https://doi.org/10.3390/molecules190913161
Mowbray SL, Kathiravan MK, Pandey AA, Odell LR. Inhibition of Glutamine Synthetase: A Potential Drug Target in Mycobacterium tuberculosis. Molecules. 2014; 19(9):13161-13176. https://doi.org/10.3390/molecules190913161
Chicago/Turabian StyleMowbray, Sherry L., Muthu K. Kathiravan, Abhishek A. Pandey, and Luke R. Odell. 2014. "Inhibition of Glutamine Synthetase: A Potential Drug Target in Mycobacterium tuberculosis" Molecules 19, no. 9: 13161-13176. https://doi.org/10.3390/molecules190913161