Rumphellaones B and C, New 4,5-Seco-Caryophyllane Sesquiterpenoids from Rumphella
Abstract
:1. Introduction
2. Results and Discussion
Position | δH (J in Hz) | δC, Multiple | 1H–1H COSY | HMBC |
---|---|---|---|---|
1 | 2.78 dd (9.2, 8.4) | 48.0, CH | H-2, H-9 | C-2, -3, -8, -9, -11, -14, -15 |
2 | 6.77 dd (16.0, 8.4) | 147.1, CH | H-1, H-3 | C-4, -9 |
3 | 6.09 d (16.0) | 131.4, CH | H-2 | C-1, -4 |
4 | 198.1, C | |||
5 | 176.7, C | |||
6 | 2.51–2.68 m | 29.1, CH2 | H2-7 | C-5 |
7 | 1.85–2.02 m | 30.9, CH2 | H2-6 | C-5, -6 |
8 | 86.6, C | |||
9 | 2.39 m | 43.0, CH | H-1, H2-10 | C-1, -2, -10 |
10 | 1.51–1.70 m | 33.1, CH2 | H-9 | C-1, -8, -9, -11, -14, -15 |
11 | 36.0, C | |||
12 | 2.25 s | 27.4, CH3 | C-3, -4 | |
13 | 1.25 s | 24.6, CH3 | C-7, -8, -9 | |
14 | 1.04 s | 23.8, CH3 | C-1, -10, -11, -15 | |
15 | 1.10 s | 29.6, CH3 | C-1, -10, -11, -14 |
Position | δH (J in Hz) | δC, Multiple | 1H–1H COSY | HMBC |
---|---|---|---|---|
1 | 1.90 m | 44.0, CH | H2-2, H-9 | C-10, -11, -15 |
2 | 1.62 m | 24.9, CH2 | H-1, H2-3 | C-1, -3, -4, -9, -11 |
3 | 2.36 t (7.2) | 41.8, CH2 | H2-2 | C-1, -2, -4 |
4 | 208.6, C | |||
5 | 177.6, C | |||
6 | 2.54 ddd (18.0, 10.8, 5.2) | 29.7, CH2 | H2-7 | C-5, -7 |
2.71 ddd (18.0, 10.8, 7.6) | ||||
7 | 1.94 ddd (14.2, 10.8, 7.6) | 25.6, CH2 | H2-6 | C-5, -8, -9, -13 |
2.20 ddd (14.2, 10.8, 5.2) | ||||
8 | 89.5, C | |||
9 | 2.12 ddd (10.0, 10.0, 9.6) | 40.2, CH | H-1, H2-10 | n. o. a |
10 | 1.43 dd (10.4, 10.0) | 33.0, CH2 | H-9 | C-1, -8, -9, -11, -14, -15 |
1.57 dd (10.4, 9.6) | ||||
11 | 33.5, C | |||
12 | 2.12 s | 30.0, CH3 | C-3, -4 | |
13 | 3.43 d (11.6) | 66.6, CH2 | C-7, -8 | |
3.73 d (11.6) | ||||
14 | 1.03 s | 22.5, CH3 | C-1, -10, -11, -15 | |
15 | 1.07 s | 30.8, CH3 | C-1, -10, -11, -14 |
3. Experimental Section
3.1. General Experimental Procedures
3.2. Animal Material
3.3. Extraction and Isolation
3.4. Generation of Superoxide Anions and Release of Elastase by Human Neutrophils
4. Conclusions
Acknowledgments
Author Contributions
Conflicts of Interest
References
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- Samples Availability: Samples of the compounds are not available from the authors.
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Chung, H.-M.; Wang, W.-H.; Hwang, T.-L.; Li, J.-J.; Fang, L.-S.; Wu, Y.-C.; Sung, P.-J. Rumphellaones B and C, New 4,5-Seco-Caryophyllane Sesquiterpenoids from Rumphella . Molecules 2014, 19, 12320-12327. https://doi.org/10.3390/molecules190812320
Chung H-M, Wang W-H, Hwang T-L, Li J-J, Fang L-S, Wu Y-C, Sung P-J. Rumphellaones B and C, New 4,5-Seco-Caryophyllane Sesquiterpenoids from Rumphella . Molecules. 2014; 19(8):12320-12327. https://doi.org/10.3390/molecules190812320
Chicago/Turabian StyleChung, Hsu-Ming, Wei-Hsien Wang, Tsong-Long Hwang, Jan-Jung Li, Lee-Shing Fang, Yang-Chang Wu, and Ping-Jyun Sung. 2014. "Rumphellaones B and C, New 4,5-Seco-Caryophyllane Sesquiterpenoids from Rumphella " Molecules 19, no. 8: 12320-12327. https://doi.org/10.3390/molecules190812320