Abstract: Bis-naphtho-γ-pyrones are an important group of aromatic polyketides derived from fungi. They have a variety of biological activities including cytotoxic, antitumor, antimicrobial, tyrosine kinase and HIV-1 integrase inhibition properties, demonstrating their potential applications in medicine and agriculture. At least 59 bis-naphtho-γ-pyrones from fungi have been reported in the past few decades. This mini-review aims to briefly summarize their occurrence, biosynthesis, and structure, as well as their biological activities. Some considerations regarding to synthesis, production, and medicinal and agricultural applications of bis-naphtho-γ-pyrones are also discussed.
This is an open access article distributed under the
Creative Commons Attribution License which permits unrestricted use, distribution,
and reproduction in any medium, provided the original work is properly cited.
Export to BibTeX
MDPI and ACS Style
Lu, S.; Tian, J.; Sun, W.; Meng, J.; Wang, X.; Fu, X.; Wang, A.; Lai, D.; Liu, Y.; Zhou, L. Bis-naphtho-γ-pyrones from Fungi and Their Bioactivities. Molecules 2014, 19, 7169-7188.
Lu S, Tian J, Sun W, Meng J, Wang X, Fu X, Wang A, Lai D, Liu Y, Zhou L. Bis-naphtho-γ-pyrones from Fungi and Their Bioactivities. Molecules. 2014; 19(6):7169-7188.
Lu, Shiqiong; Tian, Jin; Sun, Weibo; Meng, Jiajia; Wang, Xiaohan; Fu, Xiaoxiang; Wang, Ali; Lai, Daowan; Liu, Yang; Zhou, Ligang. 2014. "Bis-naphtho-γ-pyrones from Fungi and Their Bioactivities." Molecules 19, no. 6: 7169-7188.