Molecules 2014, 19(4), 4560-4577; doi:10.3390/molecules19044560
Article

Seasonal Variation of the Chemical Composition and Antimicrobial and Cytotoxic Activities of the Essential Oils from Inga laurina (Sw.) Willd.

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Received: 31 January 2014; in revised form: 26 March 2014 / Accepted: 2 April 2014 / Published: 11 April 2014
(This article belongs to the Section Metabolites)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: The seasonal chemical composition of essential oils from Inga laurina was determined by GC/MS. In the stem bark’s essential oil extracted during the dry season, the presence of terpenoids (30.05%) stood out, and phytol (9.76%) was the major compound identified. For the stem bark oil obtained during the rainy season, in addition to terpenoids (26.63%), a large amount of fatty acids (46.84%) were identified, in particular palmitic acid (25.40%). Regarding the leaves’ essential oil obtained in the dry season, esters (42.35%) were the main components. The main ester present was (Z)-hex-3-enyl benzoate (10.15%) and the major compound of this oil was (Z)-hex-3-en-1-ol (14.23%). Terpenoids (33.84%), long-chain alkanes (27.04%) and fatty acids (21.72%) were the main components of the essential oil from leaves in the rainy season. Phytol (33.21%), nonacosane (21.95%) and palmitic acid (15.20%) were the major compounds identified. The antimicrobial activity against aerobic and anaerobic oral bacteria was evaluated by the microdilution broth method and cytotoxic activity was carried out with Vero cells. The essential oils from the rainy season showed a better inhibition of the bacterial growth with Minimal Inhibitory Concentrations (MIC) values of 25 or 50 µg·mL−1 for aerobic bacteria, and high selectivity against bacteria was observed. The large amount of fatty acids in rainy season oils may be related to the better inhibitory effects observed.
Keywords: Inga laurina (Sw.) Willd.; Leguminosae; essential oil; antimicrobial activity; cytotoxic activity
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MDPI and ACS Style

Furtado, F.B.; de Aquino, F.J.T.; Nascimento, E.A.; Martins, C.M.; de Morais, S.A.L.; Chang, R.; Cunha, L.C.S.; Leandro, L.F.; Martins, C.H.G.; Martins, M.M.; Silva, C.V.; Machado, F.C.; de Oliveira, A. Seasonal Variation of the Chemical Composition and Antimicrobial and Cytotoxic Activities of the Essential Oils from Inga laurina (Sw.) Willd.. Molecules 2014, 19, 4560-4577.

AMA Style

Furtado FB, de Aquino FJT, Nascimento EA, Martins CM, de Morais SAL, Chang R, Cunha LCS, Leandro LF, Martins CHG, Martins MM, Silva CV, Machado FC, de Oliveira A. Seasonal Variation of the Chemical Composition and Antimicrobial and Cytotoxic Activities of the Essential Oils from Inga laurina (Sw.) Willd.. Molecules. 2014; 19(4):4560-4577.

Chicago/Turabian Style

Furtado, Fabiana B.; de Aquino, Francisco J.T.; Nascimento, Evandro A.; Martins, Carla M.; de Morais, Sérgio A.L.; Chang, Roberto; Cunha, Luís C.S.; Leandro, Luís F.; Martins, Carlos H.G.; Martins, Mário M.; Silva, Claudio V.; Machado, Fabrício C.; de Oliveira, Alberto. 2014. "Seasonal Variation of the Chemical Composition and Antimicrobial and Cytotoxic Activities of the Essential Oils from Inga laurina (Sw.) Willd.." Molecules 19, no. 4: 4560-4577.

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