A Novel DNA Nanosensor Based on CdSe/ZnS Quantum Dots and Synthesized Fe3O4 Magnetic Nanoparticles
Abstract
:1. Introduction
2. Results and Discussion
3. Experimental
3.1. Synthesis of Fe3O4 Magnetic Nanoparticles
3.2. Characterization of MNPs
3.3. Nucleic Acid Sequences
3.4. Surface Modification of Nanoparticles
3.5. Immobilization of DNA Sequences
3.6. DNA Hybridization
4. Conclusions
- Improve the biocompatibility and chemical stability, and tailor the dispersability and water solubility.
- Endow the iron oxide new physico-chemical properties, such as magnetic-optical properties, magnetic-electrical properties, magnetic-thermal properties, etc.
- Provide the iron oxide new functional end groups for the subsequent functionalized procedures or the subsequent applications, such as conjugation with the DNA, antibody, protein, etc.
Acknowledgments
Conflicts of Interest
References
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Hushiarian, R.; Yusof, N.A.; Abdullah, A.H.; Ahmad, S.A.A.; Dutse, S.W. A Novel DNA Nanosensor Based on CdSe/ZnS Quantum Dots and Synthesized Fe3O4 Magnetic Nanoparticles. Molecules 2014, 19, 4355-4368. https://doi.org/10.3390/molecules19044355
Hushiarian R, Yusof NA, Abdullah AH, Ahmad SAA, Dutse SW. A Novel DNA Nanosensor Based on CdSe/ZnS Quantum Dots and Synthesized Fe3O4 Magnetic Nanoparticles. Molecules. 2014; 19(4):4355-4368. https://doi.org/10.3390/molecules19044355
Chicago/Turabian StyleHushiarian, Roozbeh, Nor Azah Yusof, Abdul Halim Abdullah, Shahrul Ainliah Alang Ahmad, and Sabo Wada Dutse. 2014. "A Novel DNA Nanosensor Based on CdSe/ZnS Quantum Dots and Synthesized Fe3O4 Magnetic Nanoparticles" Molecules 19, no. 4: 4355-4368. https://doi.org/10.3390/molecules19044355